Jarmundowicz W, Tosik D, Chlebiński J, Górkiewicz Z
Kliniki Chirurgii Urazowej, Ortopedii i Neurochirurgii Wojskowego Szpitala Klinicznego we Wrocławiu.
Neurol Neurochir Pol. 1997 Nov-Dec;31(6):1167-75.
The purpose of the study was the assessment of the effect of compression of the spinal cord after traumatic injury on spinal microcirculation disturbances and the evaluation in what degree early decompression of the cord reduces the degree of these changes. The experimental study was carried out on 20 rabbits. The injury to the cord was produced at the Th9-Th10 level with simultaneous compression causing vertebral canal narrowing by 1/3 of its width. The assessment was based on the results of microangiographic qualitative and quantitative studies. The animals were divided into 4 groups depending on the duration of cord compression 2, 4, 6 and 12 hours. In each group microcirculation studies were done 12 hours after decompression. Prolonged compression was found to increase the extent of microcirculation disturbances, which were most pronounced after 6 hours of compression. In the group of 12-hour compression microcirculation improvement was observed near the focal lesion. It is concluded that possibly early decompression up to 6 hours after trauma can reduce the degree of secondary damage caused by ischaemia.
本研究的目的是评估创伤性损伤后脊髓受压对脊髓微循环障碍的影响,并评估脊髓早期减压能在何种程度上减轻这些变化的程度。对20只兔子进行了实验研究。在胸9 - 胸10水平造成脊髓损伤,同时进行压迫,使椎管狭窄至其宽度的1/3。评估基于微血管造影定性和定量研究的结果。根据脊髓受压的持续时间将动物分为4组,分别为2小时、4小时、6小时和12小时。每组在减压12小时后进行微循环研究。发现长时间压迫会增加微循环障碍的程度,在压迫6小时后最为明显。在12小时压迫组中,在局灶性病变附近观察到微循环改善。得出的结论是,创伤后6小时内尽早减压可能会减轻缺血引起的继发性损伤程度。