用流产布鲁氏菌19株保护小鼠免受血液原虫微小巴贝斯虫的侵害。
Protection of mice against haemoprotozoan Babesia microti with Brucella abortus strain 19.
作者信息
Herod E, Clark I A, Allison A C
出版信息
Clin Exp Immunol. 1978 Mar;31(3):518-23.
Abstract
When Brucella abortus strain 19 is given intraperitoneally to mice it protects them against subsequent infection with large doses of Babesia microti. The protection obtained was more effective when B. abortus was given intraperitoneally than when it was injected subcutaneously. This non-specific protection seems to be best explained by the stimulation of macrophages so as to release a mediator which limits the intracellular replication of the parasites.
摘要
将布鲁氏菌流产菌株19腹腔注射给小鼠后，可保护它们免受随后大剂量微小巴贝斯虫的感染。与皮下注射相比，腹腔注射布鲁氏菌流产菌株时获得的保护效果更佳。这种非特异性保护似乎最好的解释是巨噬细胞受到刺激从而释放一种可限制寄生虫细胞内复制的介质。
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