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用流产布鲁氏菌19株保护小鼠免受血液原虫微小巴贝斯虫的侵害。

Protection of mice against haemoprotozoan Babesia microti with Brucella abortus strain 19.

作者信息

Herod E, Clark I A, Allison A C

出版信息

Clin Exp Immunol. 1978 Mar;31(3):518-23.

PMID:95914
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1541244/
Abstract

When Brucella abortus strain 19 is given intraperitoneally to mice it protects them against subsequent infection with large doses of Babesia microti. The protection obtained was more effective when B. abortus was given intraperitoneally than when it was injected subcutaneously. This non-specific protection seems to be best explained by the stimulation of macrophages so as to release a mediator which limits the intracellular replication of the parasites.

摘要

将布鲁氏菌流产菌株19腹腔注射给小鼠后，可保护它们免受随后大剂量微小巴贝斯虫的感染。与皮下注射相比，腹腔注射布鲁氏菌流产菌株时获得的保护效果更佳。这种非特异性保护似乎最好的解释是巨噬细胞受到刺激从而释放一种可限制寄生虫细胞内复制的介质。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c86/1541244/be960affe719/clinexpimmunol00229-0183-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c86/1541244/be960affe719/clinexpimmunol00229-0183-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c86/1541244/be960affe719/clinexpimmunol00229-0183-a.jpg

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Suggested importance of monokines in pathophysiology of endotoxin shock and malaria.
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本文引用的文献

1
Interferon Induction and Resistance to Virus Infection in Mice Infected with Brucella abortus.感染布鲁氏菌的小鼠中干扰素的诱导和对病毒感染的抵抗。
Infect Immun. 1970 Dec;2(6):698-704. doi: 10.1128/iai.2.6.698-704.1970.
2
The role of the reticuloendothelial system in the host reaction to neoplasia.网状内皮系统在宿主对肿瘤形成的反应中的作用。
Cancer Res. 1961 Oct;21:1281-300.
3
MACROPHAGE PROLIFERATION IN RELATION TO ACQUIRED CELLULAR RESISTANCE.巨噬细胞增殖与获得性细胞抗性的关系
Infect Immun. 1985 Nov;50(2):523-6. doi: 10.1128/iai.50.2.523-526.1985.
4
Resistance to Babesia spp. and Plasmodium sp. in mice pretreated with an extract of Coxiella burnetii.用伯纳特立克次体提取物预处理的小鼠对巴贝斯虫属和疟原虫的抗性。
Infect Immun. 1979 May;24(2):319-25. doi: 10.1128/iai.24.2.319-325.1979.
Aust J Exp Biol Med Sci. 1964 Dec;42:707-16. doi: 10.1038/icb.1964.67.
4
THE IMMUNOLOGICAL BASIS OF ACQUIRED CELLULAR RESISTANCE.获得性细胞抗性的免疫学基础。
J Exp Med. 1964 Jul 1;120(1):105-20. doi: 10.1084/jem.120.1.105.
5
[ADJUVANT PROPERTIES OF CORYNEBACTERIUM PARVUM ON ANTIBODY PRODUCTION AND ON THE INDUCTION OF DELAYED HYPERSENSITIVITY TOWARD CONJUGATED PROTEINS].短小棒状杆菌对抗体产生及对结合蛋白迟发型超敏反应诱导的佐剂特性
Ann Inst Pasteur (Paris). 1964 May;106:771-7.
6
[PHAGOCYTIC ACTIVITY OF THE RETICULOENDOTHELIAL SYSTEM IN MICE INFECTED WITH "BRUCELLA SUIS"].
Rev Bras Biol. 1963 Jun;23:25-30.
7
The effect of Brucella abortus infection on transmissible Crocker's sarcoma in mice.流产布鲁氏菌感染对小鼠可传播性克罗克肉瘤的影响。
Acta Med Pol. 1960;1(3-4):219-41.
8
Spleen and liver reactions in young and adult mice in the course of an experimental Brucellae infection.
Pathol Microbiol (Basel). 1960;23:820-8. doi: 10.1159/000161044.
9
The effect of Mycobacterium tuberculosis (BCG) infection on the resistance of mice to bacterial endotoxin and Salmonella enteritidis infection.结核分枝杆菌（卡介苗）感染对小鼠抵抗细菌内毒素和肠炎沙门氏菌感染能力的影响。
Br J Exp Pathol. 1959 Jun;40(3):281-90.
10
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J Exp Med. 1957 Nov 1;106(5):703-17. doi: 10.1084/jem.106.5.703.