Nelson P
Department of Physics and Astronomy, University of Pennsylvania, Philadelphia 19104, USA.
Biophys J. 1998 May;74(5):2501-3. doi: 10.1016/S0006-3495(98)77958-5.
The symmetries of the DNA double helix require a new term in its linear response to stress: the coupling between twist and stretch. Recent experiments with torsionally constrained single molecules give the first direct measurement of this new material parameter. We extract its value from a recent experiment. Finally, we sketch the effect of constrained twist on entropic elasticity of DNA arising from the connection between Link, Twist, and Writhe.
DNA双螺旋的对称性要求在其对应力的线性响应中引入一个新的术语：扭曲与拉伸之间的耦合。最近对受扭转约束的单分子进行的实验首次直接测量了这个新的材料参数。我们从最近的一项实验中提取了它的值。最后，我们概述了受约束的扭曲对DNA熵弹性的影响，这种影响源于连环数、扭曲数和缠绕数之间的联系。
