Chabbert V, Ranjeva J P, Sevely A, Boetto S, Berry I, Manelfe C
Service de Neuroradiologie, Hopital Purpan, Toulouse, France.
Neuroradiology. 1998 Apr;40(4):267-71. doi: 10.1007/s002340050583.
MRI in two children with moya-moya demonstrated low signal on T2-weighted images in the acute and subacute phases of ischaemia. Gradient-echo sequences, more sensitive to magnetic susceptibility, demonstrated these abnormalities better. Signal loss, due to temporary accumulation of iron, decreases progressively and disappears in the chronic stage of the disease. Diffusion-weighted MRI allows early detection of ischaemic lesions and can be used to monitor progressive spreading of the lesions. Magnetisation transfer maps provide sharp contrast, useful for demonstrating cortical atrophy.
两名烟雾病患儿的MRI显示，在缺血的急性期和亚急性期，T2加权图像上信号较低。对磁化率更敏感的梯度回波序列能更好地显示这些异常。由于铁的暂时积聚导致的信号丢失会逐渐减少，并在疾病的慢性期消失。弥散加权MRI可早期检测缺血性病变，并可用于监测病变的进行性扩散。磁化传递图提供清晰的对比度，有助于显示皮质萎缩。
