通过放射免疫分析法测定人体受试者中前列腺素F1α和F2α的主要尿液代谢物水平。

The levels of main urinary metabolite of prostaglandin F1alpha and F2alpha in human subjects measured by radioimmunoassay.

作者信息

Ohki S, Nishigaki Y, Imaki K, Kurono M, Hirata F

出版信息

Prostaglandins. 1976 Aug;12(2):181-6. doi: 10.1016/0090-6980(76)90112-x.

Abstract

Radioimmunoassay technique for measuring 5alpha, 7alpha-dihydroxy-11-keto-tetranorprosta-1, 16-dioic acid, the main urinary metabolite of PGF1alpha and PGF2alpha (PGF2alpha-MUM), was further improved. It was postulated based on some experimental data that the PGF2alpha-MUM exists in the urine mostly as dioic acid form, not as delta-lactone form the daily excretion of PGF2alpha-MUM in men ranged from 14.43 mug to 36.14 mug and in women from 5.21 mug to 14.25 mug.

摘要

用于测量5α,7α - 二羟基 - 11 - 酮 - 四降前列腺 - 1,16 - 二酸（PGF1α和PGF2α的主要尿代谢物，即PGF2α - MUM）的放射免疫分析技术得到了进一步改进。根据一些实验数据推测，PGF2α - MUM在尿液中大多以二酸形式存在，而非δ - 内酯形式。男性PGF2α - MUM的日排泄量在14.43微克至36.14微克之间，女性则在5.21微克至14.25微克之间。