人类新生儿在冷适应过程中的睡眠改变。

Sleep modifications during cool acclimation in human neonates.

作者信息

Telliez F, Bach V, Dewasmes G, Leke A, Libert J P

机构信息

Laboratoire des Techniques d'Explorations Fonctionnelles, Faculté de Médecine, Université de Picardie Jules Verne, Amiens, France.

出版信息

Neurosci Lett. 1998 Mar 27;245(1):25-8. doi: 10.1016/s0304-3940(98)00169-4.

DOI:10.1016/s0304-3940(98)00169-4

PMID:9596347

Abstract

The present study aimed at testing in human neonates whether the thermal acclimation could reduce the sleep disturbances induced by brief cool exposure. Six neonates were exposed in incubator to a standardised cool thermal load of 75 h duration. The results show an increase of the metabolic heat production (VO2: +25% reaching 5.68 ml/min per kg) during cool acclimation which is not associated with a reduction of the sleep modifications observed on the first cool exposure: the increase of active sleep (+15%, +2 min) and the decrease of quiet sleep (-15%, -11 min) persist and wakefulness after sleep onset increases (+12%, +10 min). In conclusion, there is no sleep adaptation as cool acclimation progressed.

摘要

本研究旨在测试人类新生儿的热适应是否能减少短暂冷暴露引起的睡眠干扰。六名新生儿在培养箱中暴露于持续75小时的标准化冷热负荷下。结果显示，在冷适应过程中，代谢产热增加（VO2：增加25%，达到每千克每分钟5.68毫升），但这与首次冷暴露时观察到的睡眠改变减少无关：主动睡眠增加（+15%，增加2分钟），安静睡眠减少（-15%，减少11分钟）持续存在，睡眠开始后的清醒时间增加（+12%，增加10分钟）。总之，随着冷适应的进展，没有睡眠适应现象。