Mathews K A
Emergency and Critical Care Service, Veterinary Teaching Hospital, Ontario Veterinary College, University of Guelph, Canada.
Vet Clin North Am Small Anim Pract. 1998 May;28(3):483-513. doi: 10.1016/s0195-5616(98)50052-6.
Assessment of hydration and perfusion is essential in patient evaluation. The acid-base and electrolyte disturbances that accompany many illnesses should also be considered. The duration of illness and body systems involved are also of major importance in patient evaluation. Fluid therapy is an important and potentially life-saving treatment of many and varied problems. The clinician must be able to assess the patient and determine whether the intravascular or extravascular compartments, or both, are deficient. Of primary concern is the status of the intravascular volume, then restoration of total body water and electrolytes. Fluid therapy is divided into three phases; the emergency phase, the rehydration phase, and the maintenance phase; not all patients require the three-phase therapy. The clinician must also be able to select (1) the appropriate solution to treat the volume deficit and correct the acid-base and electrolyte abnormalities and (2) the rate of administration to optimize outcome. Therefore, knowledge of electrolyte composition in plasma and of the various types of commercially available fluids is essential in order to select the appropriate therapy for the individual animal. In addition to the therapeutic aspects of fluid therapy, a knowledge of the side effects and complications of inappropriate fluid selection and rate of delivery is also important. With the individual requirements of each patient seen in a practice, the prescription approach to parenteral fluid therapy will optimize patient response to this extremely important aspect of overall patient management as well as make the practice of fluid therapy intellectually stimulating. This article has introduced the clinician to the parenteral fluids available and their indications in veterinary patients; it also contains a discussion of how to utilize preferred solutions for treatment of specific diseased states. Although there are definite "right" and "wrong" fluids to select for specific problems, there also remains individual preference in fluid choice, which is based on appropriate laboratory data and the practitioner's clinical judgment of the status of the individual patient vis-à-vis the spectrum of its disease. Recommendations for selection of different fluid types to treat similar conditions are usually based on these variables.
评估水合作用和灌注情况对患者评估至关重要。许多疾病伴随的酸碱和电解质紊乱也应予以考虑。疾病持续时间和受累身体系统在患者评估中也非常重要。液体疗法是治疗多种不同问题的重要且可能挽救生命的治疗方法。临床医生必须能够评估患者并确定血管内或血管外间隙,或两者是否存在不足。首要关注的是血管内容量状态,然后是全身水和电解质的恢复。液体疗法分为三个阶段:紧急阶段、补液阶段和维持阶段;并非所有患者都需要三相疗法。临床医生还必须能够选择:(1)合适的溶液来治疗容量不足并纠正酸碱和电解质异常;(2)给药速度以优化治疗效果。因此,了解血浆中的电解质组成以及各种市售液体类型对于为个体动物选择合适的治疗方法至关重要。除了液体疗法的治疗方面,了解不适当的液体选择和给药速度的副作用及并发症也很重要。根据临床实践中所见每个患者的个体需求,肠外液体疗法的处方方法将优化患者对整体患者管理这一极其重要方面的反应,同时使液体疗法的实践具有智力挑战性。本文向临床医生介绍了可用的肠外液体及其在兽医患者中的适应症;它还讨论了如何使用首选溶液治疗特定疾病状态。尽管针对特定问题有明确的“正确”和“错误”液体可供选择,但在液体选择上仍存在个人偏好,这基于适当的实验室数据以及从业者对个体患者病情状况的临床判断。针对治疗相似病症选择不同液体类型的建议通常基于这些变量。