Posset U, Löcklin E, Thull R, Kiefer W
Lehrstuhl und Abteilung für Experimentelle Zahnmedizin, Klinik und Poliklinik für Zahn-, Mund- und Kieferkrankheiten, Universität Würzburg, Germany.
J Biomed Mater Res. 1998 Jun 15;40(4):640-5. doi: 10.1002/(sici)1097-4636(19980615)40:4<640::aid-jbm16>3.0.co;2-j.
Polycrystalline tetracalcium phosphate (TTCP), a material of considerable interest for human implantation due to its similarity to hydroxyapatite, was studied by means of Raman and FT-IR spectroscopy. The spectra were interpreted on the basis of group theoretical considerations. In addition, the setting reaction of a calcium phosphate cement (CPC) consisting of an equimolar mixture of TTCP and dicalcium phosphate (DCPA) was investigated by Raman spectroscopy. The band of the totally symmetric phosphate mode v1 of TTCP showed marked factor group splittings. The splitting components arose at coincident wave numbers in the IR and Raman spectra. This observation was in accordance with space group P2(1) (factor group C2(2), Z = 4). The characteristic splitting of v1 allowed the setting reaction of CPC to hydroxyapatite to be followed. According to the Raman spectroscopic results, considerable amounts of TTCP must be present at the sample surface after 24 h of setting in an aqueous environment.
多晶磷酸四钙（TTCP）因其与羟基磷灰石相似而成为一种备受关注的用于人体植入的材料，通过拉曼光谱和傅里叶变换红外光谱对其进行了研究。基于群论考虑对光谱进行了解释。此外，通过拉曼光谱研究了由TTCP和磷酸二钙（DCPA）等摩尔混合物组成的磷酸钙骨水泥（CPC）的凝固反应。TTCP的全对称磷酸根模式v1的谱带显示出明显的因子群分裂。分裂成分在红外光谱和拉曼光谱的重合波数处出现。这一观察结果与空间群P2(1)（因子群C2(2)，Z = 4）一致。v1的特征分裂使得能够追踪CPC向羟基磷灰石的凝固反应。根据拉曼光谱结果，在水环境中凝固24小时后，样品表面必须存在大量的TTCP。
