Liotti M, Ryder K, Woldorff M G
Electrophysiological Imaging Division, University of Texas Health Science Center at San Antonio 78264, USA.
Neuroreport. 1998 Apr 20;9(6):1007-12. doi: 10.1097/00001756-199804200-00010.
Functional reorganization of auditory attention was studied in 12 congenitally blind subjects and 12 controls using high-density event-related potentials during a highly focused dichotic listening task. Reaction times for the attend-ear intensity-deviant targets were markedly faster for the blind. Brain activity associated with sustained attention (N1 effect, Nd), and with the automatic detection of deviants in an unattended channel (MMN), did not exhibit reorganization. In contrast, marked plasticity changes were reflected in late auditory attentional processing (attend-ear targets), in the form of a prolonged negativity (200-450 ms post-stimulus) that was absent in the sighted subjects. The plasticity changes in the blind had a time course indicating progressive recruitment of parietal and then occipital regions, providing new evidence for cross-modal sensory reorganization in the blind.
在一项高度集中的双耳分听任务中，使用高密度事件相关电位对12名先天性盲人受试者和12名对照组进行了听觉注意力的功能重组研究。盲人对注意耳强度异常目标的反应时间明显更快。与持续注意力相关的大脑活动（N1效应、Nd）以及与未注意通道中异常刺激的自动检测相关的大脑活动（MMN）均未表现出重组。相比之下，晚期听觉注意力处理（注意耳目标）中出现了明显的可塑性变化，表现为一种延长的负电位（刺激后200 - 450毫秒），而有视力的受试者中不存在这种情况。盲人的可塑性变化具有一定的时间进程，表明顶叶区域随后是枕叶区域逐渐被招募，为盲人的跨模态感觉重组提供了新证据。
