Casanova D, Bardot J, Andrac-Meyer L, Magalon G
Department of Plastic, Reconstructive and Cosmetic Surgery, Hôpital de la Conception, Marseilles, France.
Br J Dermatol. 1998 Feb;138(2):341-5. doi: 10.1046/j.1365-2133.1998.02088.x.
Early curettage of giant congenital naevi in new-born infants, if performed during the first few weeks after birth, can have a substantial effect on the pigmentation of the lesions, reducing the number of pigmented cells and leaving only moderate scars. We describe our experience in a series of nine congenital naevi treated by curettage between the first and seventh week after birth. Histological changes that occur in the naevus during the first few days after birth mean that early treatment is needed to obtain a cosmetic improvement. Curettage as an early treatment for giant congenital naevi in new-born infants provides cosmetic improvement and might decrease the risk of malignancy; however, the lesions are not cured. Naevus cells persist in the deep dermal layers and may come to the surface, such that close monitoring is needed long after curettage. The cosmetic improvement is likely to benefit the child's psychological development.
如果在新生儿出生后的头几周内对巨大先天性痣进行早期刮除术,可对病变的色素沉着产生显著影响,减少色素细胞数量,仅留下中度疤痕。我们描述了在出生后第一周至第七周期间通过刮除术治疗的一系列九例先天性痣的经验。出生后头几天痣内发生的组织学变化意味着需要早期治疗才能获得美容改善。刮除术作为新生儿巨大先天性痣的早期治疗方法可改善外观,并可能降低恶变风险;然而,病变并未治愈。痣细胞持续存在于真皮深层,可能会出现在表面,因此在刮除术后很长一段时间都需要密切监测。外观的改善可能有利于儿童的心理发育。