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1
Evaluation of lacticin 3147 and a teat seal containing this bacteriocin for inhibition of mastitis pathogens.评估乳酸链球菌素3147及一种含有该细菌素的乳头封闭剂对乳腺炎病原体的抑制作用。
Appl Environ Microbiol. 1998 Jun;64(6):2287-90. doi: 10.1128/AEM.64.6.2287-2290.1998.
2
Efficacy of a teat dip containing the bacteriocin lacticin 3147 to eliminate Gram-positive pathogens associated with bovine mastitis.含抑菌素乳链菌肽 3147 的药浴液对消除奶牛乳腺炎相关革兰氏阳性病原体的效果。
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3
Protection against Staphylococcus aureus mastitis in dairy cows using a bismuth-based teat seal containing the bacteriocin, lacticin 3147.使用含有细菌素乳酸链球菌素3147的铋基乳头封闭剂预防奶牛金黄色葡萄球菌性乳腺炎
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The natural food grade inhibitor, lacticin 3147, reduced the incidence of mastitis after experimental challenge with Streptococcus dysgalactiae in nonlactating dairy cows.天然食品级抑制剂乳酸链球菌素3147降低了非泌乳期奶牛经乳房链球菌实验性攻毒后乳腺炎的发病率。
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The natural food grade inhibitor, lacticin 3147, reduced the incidence of mastitis after experimental challenge with Streptococcus dysgalactiae in nonlactating dairy cows.天然食品级抑制剂乳酸链球菌素3147可降低非泌乳奶牛经乳房链球菌实验性攻毒后乳腺炎的发病率。
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In vitro antimicrobial effect and in vivo preventive and therapeutic effects of partially purified lantibiotic lacticin NK34 against infection by Staphylococcus species isolated from bovine mastitis.体外抗菌作用及部分纯化乳链菌肽 NK34 对奶牛乳腺炎分离的金黄色葡萄球菌感染的体内预防和治疗作用。
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Antibacterial activities of coagulase-negative staphylococci from bovine teat apex skin and their inhibitory effect on mastitis-related pathogens.来自牛乳头顶端皮肤的凝固酶阴性葡萄球菌的抗菌活性及其对乳腺炎相关病原体的抑制作用。
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Efficacy of bacteriocin-based formula for reducing staphylococci, streptococci, and total bacterial counts on teat skin of dairy cows.基于细菌素的配方对减少奶牛乳头皮肤上葡萄球菌、链球菌和总细菌数的功效。
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Efficacy of a 0.1% iodine teat dip against Staphylococcus aureus and Streptococcus agalactiae during experimental challenge.0.1%碘乳头浸液在实验性攻毒期间对金黄色葡萄球菌和无乳链球菌的疗效。
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Antibiotics (Basel). 2023 Jul 30;12(8):1256. doi: 10.3390/antibiotics12081256.
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Emulsion-Based Postbiotic Formulation Is Comparable to Viable Cells in Eliciting a Localized Immune Response in Dairy Cows With Chronic Mastitis.基于乳剂的后生元制剂在引发慢性乳腺炎奶牛的局部免疫反应方面与活细胞相当。
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本文引用的文献

1
Lacticin 3147, a broad-spectrum bacteriocin which selectively dissipates the membrane potential.Lacticin 3147，一种能选择性消除膜电位的广谱细菌素。
Appl Environ Microbiol. 1998 Feb;64(2):439-45. doi: 10.1128/AEM.64.2.439-445.1998.
2
Application and evaluation of the phage resistance- and bacteriocin-encoding plasmid pMRC01 for the improvement of dairy starter cultures.用于改良乳制品发酵剂的抗噬菌体和编码细菌素的质粒pMRC01的应用与评价
Appl Environ Microbiol. 1997 Apr;63(4):1434-40. doi: 10.1128/aem.63.4.1434-1440.1997.
3
An application in cheddar cheese manufacture for a strain of Lactococcus lactis producing a novel broad-spectrum bacteriocin, lacticin 3147.一株产新型广谱细菌素——乳酸乳球菌素3147的乳酸乳球菌在切达干酪生产中的应用。
Appl Environ Microbiol. 1996 Feb;62(2):612-9. doi: 10.1128/aem.62.2.612-619.1996.
4
Efficacy and financial value of antibiotic treatment of bovine clinical mastitis during lactation--a review.泌乳期奶牛临床型乳房炎抗生素治疗的疗效与经济价值——综述
Br Vet J. 1987 Sep-Oct;143(5):410-22. doi: 10.1016/0007-1935(87)90018-2.
5
Nisin inhibits several gram-positive, mastitis-causing pathogens.乳酸链球菌素可抑制多种革兰氏阳性、引起乳腺炎的病原体。
J Dairy Sci. 1989 Dec;72(12):3342-5. doi: 10.3168/jds.S0022-0302(89)79496-0.
6
Lysostaphin: use of a recombinant bactericidal enzyme as a mastitis therapeutic.溶葡萄球菌酶：一种重组杀菌酶作为乳腺炎治疗剂的应用。
J Dairy Sci. 1991 Dec;74(12):4175-82. doi: 10.3168/jds.S0022-0302(91)78612-8.
7
Influence of fat and emulsifiers on the efficacy of nisin in inhibiting Listeria monocytogenes in fluid milk.脂肪和乳化剂对乳酸链球菌素抑制液态奶中单核细胞增生李斯特菌效果的影响。
J Dairy Sci. 1992 Feb;75(2):387-93. doi: 10.3168/jds.S0022-0302(92)77773-X.

评估乳酸链球菌素3147及一种含有该细菌素的乳头封闭剂对乳腺炎病原体的抑制作用。

Evaluation of lacticin 3147 and a teat seal containing this bacteriocin for inhibition of mastitis pathogens.

作者信息

Ryan M P, Meaney W J, Ross R P, Hill C

机构信息

Dairy Products Research Centre, Teagasc, Moorepark, Fermoy, County Cork, Ireland.

出版信息

Appl Environ Microbiol. 1998 Jun;64(6):2287-90. doi: 10.1128/AEM.64.6.2287-2290.1998.

DOI:10.1128/AEM.64.6.2287-2290.1998
PMID:9603853
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC106317/
Abstract

Lacticin 3147 is a broad-spectrum bacteriocin produced by Lactococcus lactis subsp. lactis DPC3147 which is bactericidal against a range of mastitis-causing streptococci and staphylococci. In this study, both lacticin 3147 and the lantibiotic nisin were separately incorporated into an intramammary teat seal product. The seal containing lacticin 3147 exhibited excellent antimicrobial activity and might form the basis of an improved treatment for the prevention of mastitis in dry cows.

摘要

Lacticin 3147是一种由乳酸乳球菌乳酸亚种DPC3147产生的广谱细菌素，它对一系列引起乳腺炎的链球菌和葡萄球菌具有杀菌作用。在本研究中，Lacticin 3147和羊毛硫抗生素乳链菌肽分别被添加到一种乳房内乳头封闭产品中。含有Lacticin 3147的封闭剂表现出优异的抗菌活性，可能为改进干奶牛乳腺炎预防治疗方法奠定基础。