Ryan M P, Meaney W J, Ross R P, Hill C
Dairy Products Research Centre, Teagasc, Moorepark, Fermoy, County Cork, Ireland.
Appl Environ Microbiol. 1998 Jun;64(6):2287-90. doi: 10.1128/AEM.64.6.2287-2290.1998.
Lacticin 3147 is a broad-spectrum bacteriocin produced by Lactococcus lactis subsp. lactis DPC3147 which is bactericidal against a range of mastitis-causing streptococci and staphylococci. In this study, both lacticin 3147 and the lantibiotic nisin were separately incorporated into an intramammary teat seal product. The seal containing lacticin 3147 exhibited excellent antimicrobial activity and might form the basis of an improved treatment for the prevention of mastitis in dry cows.
Lacticin 3147是一种由乳酸乳球菌乳酸亚种DPC3147产生的广谱细菌素,它对一系列引起乳腺炎的链球菌和葡萄球菌具有杀菌作用。在本研究中,Lacticin 3147和羊毛硫抗生素乳链菌肽分别被添加到一种乳房内乳头封闭产品中。含有Lacticin 3147的封闭剂表现出优异的抗菌活性,可能为改进干奶牛乳腺炎预防治疗方法奠定基础。