带状疱疹感染后出现结节性多动脉炎样特征的皮肤肉芽肿性血管炎。

Cutaneous granulomatous vasculitis after herpes zoster infection showing polyarteritis nodosa-like features.

作者信息

Rodríguez-Pereira C, Suárez-Peñaranda J M, del Río E, Forteza-Vila J

机构信息

Department of Pathology, Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain.

出版信息

Clin Exp Dermatol. 1997 Nov;22(6):274-6.

PMID:9604453

Abstract

Various cutaneous lesions have been described after herpes zoster infection, such as lymphomas, pseudolymphoma and granulomatous conditions (granuloma annulare, tuberculoid granuloma, sarcoidosis). However, granulomatous vasculitis is an extremely rare sequel. We now describe a case of superficial granulomatous vasculitis with deep 'polyarteritis nodosa (PAN)-like' arteritis that developed after herpes zoster infection. Polymerase chain reaction did not detect genome of the herpes virus. We suggest that this condition could be an immune response to viral proteins.

摘要

带状疱疹感染后曾有多种皮肤病变的描述，如淋巴瘤、假性淋巴瘤和肉芽肿性疾病（环状肉芽肿、结核样肉芽肿、结节病）。然而，肉芽肿性血管炎是一种极其罕见的后遗症。我们现报告1例带状疱疹感染后发生的浅表性肉芽肿性血管炎伴深部“结节性多动脉炎（PAN）样”动脉炎的病例。聚合酶链反应未检测到疱疹病毒基因组。我们认为这种情况可能是对病毒蛋白的免疫反应。