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精神分裂症患者的皮肤电活动与产科并发症

Electrodermal activity and obstetric complications in schizophrenia.

作者信息

Ohman A, Hultman C M

机构信息

Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden.

出版信息

J Abnorm Psychol. 1998 May;107(2):228-37. doi: 10.1037//0021-843x.107.2.228.

Abstract

The pregnancy and birth records of 79 schizophrenic patients, from whom adult electrodermal data were available, were systematically evaluated for obstetric complications using 34 criteria of nonoptimality in pregnancy, delivery, and postpartum periods. Patients with many obstetric complications had lower levels of electrodermal activity. For frequency of skin conductance responses and spontaneous fluctuations in skin conductance, the association was more evident for women than for men. However, the ratio of stimulus-elicited to spontaneous skin conductance responses showed a reliable association with obstetric complications without any gender differences. The relationship between obstetric complications and electrodermal activity was interpreted in terms of neurodevelopmental insults resulting in structural brain abnormalities interfering with orienting and electrodermal activity.

摘要

对79名有成人皮肤电数据的精神分裂症患者的妊娠和分娩记录进行了系统评估,采用34条妊娠、分娩和产后非最佳状态标准来判断产科并发症。产科并发症多的患者皮肤电活动水平较低。对于皮肤电导反应频率和皮肤电导的自发波动,女性的关联性比男性更明显。然而,刺激诱发的与自发的皮肤电导反应之比与产科并发症存在可靠关联,且无性别差异。产科并发症与皮肤电活动之间的关系被解释为神经发育损伤导致大脑结构异常,进而干扰定向和皮肤电活动。

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