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上西里西亚地区胃癌和结肠癌患者的血浆硒浓度

Plasma selenium concentration in patients with stomach and colon cancer in the Upper Silesia.

作者信息

Scieszka M, Danch A, Machalski M, Drózdz M

机构信息

I Clinic of Internal Diseases, Silesian Medical Academy, Katowice, Poland.

出版信息

Neoplasma. 1997;44(6):395-7.

PMID:9605014
Abstract

Plasma selenium concentration was assessed in 44 patients with cancer of the gastrointestinal tract (19 subjects with stomach cancer and 25 with colon cancer) and 25 age-matched healthy control subjects. Selenium concentration was determined by the fluorometric method. The observed plasma selenium concentrations in gastrointestinal cancer patients (37.0 +/- 11.05 ng Se/ml or 38.4 +/- 12.6 ng Se/ml in stomach or colon cancer patients, respectively) were significantly lower as compared to the healthy age-matched control group (51.4 +/- 14.4 ng Se/ml). The diagnosed low selenium status may be considered as a high risk for cancer development.

摘要

对44例胃肠道癌症患者(19例胃癌患者和25例结肠癌患者)以及25名年龄匹配的健康对照者进行了血浆硒浓度评估。采用荧光法测定硒浓度。胃肠道癌症患者的血浆硒浓度(胃癌患者为37.0±11.05 ng Se/ml,结肠癌患者为38.4±12.6 ng Se/ml)与年龄匹配的健康对照组(51.4±14.4 ng Se/ml)相比显著降低。诊断出的低硒状态可能被视为癌症发生的高风险因素。

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