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[乳酸菌素对菌群失调受试者上呼吸道微生物群的影响]

[Influence of lactobacterin on the upper respiratory tract microflora of subjects with microflora disorders].

作者信息

Korniushenkova I N

出版信息

Aviakosm Ekolog Med. 1998;32(1):73-7.

PMID:9606519
Abstract

High respiratory tract microflora recovery has been revealed in human subjects treated perorally with commercial Lactobacterinum. In most of the participants in the study, different (up to epidemically significant) values of disbiotic shifts including persistence of conventional pathogens (enterobacteria) and pathogenic staphylococci in high respiratory tract mucosa as well as nasopharyngeal lactoflora deficiency were observed in the pretreatment period. Significant, in the order of one to four, decreases in pathogenic microflora count up to complete elimination were accompanied by lactoflora restoration in a part of the subjects after treatment. Hence, Lactobacterinum seems to be a perspective means for correcting and optimizing the high respiratory tract microflora, especially in contingents subjected to the environmental factors with a high risk of disbiotic disorders.

摘要

口服商业乳酸杆菌制剂治疗的人体受试者呼吸道微生物群已显示出高度恢复。在该研究的大多数参与者中,在治疗前期观察到不同程度(直至具有流行病学意义)的生态失调变化,包括呼吸道黏膜中传统病原体(肠杆菌)和致病性葡萄球菌持续存在以及鼻咽部乳杆菌菌群缺乏。治疗后,部分受试者致病性微生物群数量显著减少(减少一到四个数量级直至完全消除),同时乳杆菌菌群得到恢复。因此,乳酸杆菌制剂似乎是纠正和优化呼吸道微生物群的一种有前景的手段,特别是对于面临生态失调高风险环境因素的人群。

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