Diuĭzen I V, Kalinichenko S G, Oxotin V E, Motavkin P A
Laboratory of Cytophysiology and Pharmacology, Far East Section of Russian Academy of Sciences, Vladivostok.
Morfologiia. 1998;113(1):47-51.
Distribution of nitric oxide synthase in hippocampal formation of 4 human subjects was studied using histochemical NADPH-diaphorase reaction. Two cell types (spinous and non-spinous) were distinguished. Type 1 neurons exhibit morphological features of pyramidal cells: their apical and basal dendrites are thickly covered spines throughout entire length. It is admissible that these cells are ectopic pyramidal neurons by their origin and function as acceptors of septal and associative and commissural afferents transmitted to hippocampus. Type 2 cells are morphologically heterogeneous with dipolar, multipolar and round neurons present among them. The cells are arranged either one by one or in groups, forming synaptic contacts with one another. Adjacent vessels are not only accompanied by their long varicose dendrites but are closely surrounded by their terminals. Non-spinous hippocampal neurons participate in local blood circulation by synthesizing nitric oxide--an endothelium-derived relaxation factor.
利用组织化学NADPH黄递酶反应研究了4例人体海马结构中一氧化氮合酶的分布。区分出两种细胞类型（棘状和非棘状）。1型神经元呈现锥体细胞的形态特征：其顶端和基底树突在整个长度上都密布着棘。可以认为，这些细胞在起源和功能上是异位锥体细胞，作为传递到海马体的隔区、联合和连合传入纤维的受体。2型细胞在形态上具有异质性，其中有双极、多极和圆形神经元。这些细胞单个或成群排列，相互形成突触联系。相邻血管不仅伴有其长的曲张树突，而且被其终末紧密包围。非棘状海马神经元通过合成一氧化氮（一种内皮源性舒张因子）参与局部血液循环。
