Mendling W
Klinikum Frankfurt (Oder), Akademisches Lehrkrankenhaus der Humboldt-Universität (Charite) zu Berlin.
Z Arztl Fortbild Qualitatssich. 1998 Apr;92(3):175-9.
Due to its pathogenety Candida albicans is the most frequent yeast in cases of vaginal candidosis, probably mostly caused by local immunological weakness. In 5-30% one can expect a vaginal yeast colonisation depending on age, estrogen influence, pregnancy and dispositions by illness. Prepartal vaginal yeast colonisation should be treated to protect the newborn. The only typical symptom of acute vaginal candidosis is itching. Beside history and clinical symptoms, examination of vaginal secretion by phase contrast microscopy and the yeast culture are cornerstones of the diagnosis. Antimycotic resistance should be investigated only by specialists. Acute Candida albicans vaginitis should be treated locally by one or three day therapy. Candida glabrata vaginitis can be treated with high doses of oral fluconazole.
由于其发病机制,白色念珠菌是阴道念珠菌病病例中最常见的酵母菌,可能主要由局部免疫功能低下引起。根据年龄、雌激素影响、怀孕和疾病易感性,5%至30%的人可能会出现阴道酵母菌定植。产前阴道酵母菌定植应进行治疗以保护新生儿。急性阴道念珠菌病的唯一典型症状是瘙痒。除病史和临床症状外,通过相差显微镜检查阴道分泌物和进行酵母菌培养是诊断的基石。抗真菌耐药性仅应由专家进行调查。急性白色念珠菌阴道炎应采用一日或三日局部治疗。光滑念珠菌阴道炎可用高剂量口服氟康唑治疗。