Cloning and tissue distribution of the human G protein beta 5 cDNA.
作者信息
Jones P G, Lombardi S J, Cockett M I
机构信息
Wyeth-Ayerst Research, Princeton, NJ 08543, USA.
出版信息
Biochim Biophys Acta. 1998 Apr 24;1402(3):288-91. doi: 10.1016/s0167-4889(98)00017-2.
PMID:9606987
Abstract
Heterotrimeric G proteins integrate signals between receptors and effector proteins. We have cloned the human beta 5 subunit from a human brain cDNA library. The clone has a 1059 bp open reading frame and is highly homologous to the murine clone. In contrast to the brain specific mouse beta 5, northern analysis showed it to be expressed in multiple tissues.
摘要
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