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无胃酸症中的乳酸脱氢酶同工酶与胃泌素(作者译)

[LDH isoenzymes and gastrin in achlorhydri (author's transl)].

作者信息

Mohamedi S, Penner E, Brunner H, Sinzinger H, Pietschmann H

出版信息

Wien Klin Wochenschr. 1976 Jul 16;88(14):458-60.

PMID:960704
Abstract

Several haematological findings (especially the values of serum LDH and its isoenzymes) were compared with changes in the gastrin level in pernicious anaemia. While vitamin B12 substitution therapy led to normalization of the anaemia and of the enzyme levels, gastric atrophy and, hence, the elevation in serum gastrin levels remained unchanged. Determination of serum gastrin, therefore, provides a valuable tool for the verification of the diagnosis of pernicious anaemia in treated cases.

摘要

将几种血液学检查结果(尤其是血清乳酸脱氢酶及其同工酶的值)与恶性贫血患者胃泌素水平的变化进行了比较。虽然维生素B12替代疗法使贫血和酶水平恢复正常,但胃萎缩以及血清胃泌素水平升高仍未改变。因此,血清胃泌素的测定为确诊经治疗的恶性贫血病例提供了一种有价值的手段。

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