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[使用定量血沉棕黄层(QBC)检测慢性期恰加斯病患者外周血中克氏锥虫的尝试]

[An attempt to detect Trypanosoma cruzi in the peripheral blood of patients with Chagas' disease, in chronic phase, using quantitative buffy coat (QBC)].

作者信息

Amato Neto V, Lopes M H, De Marchi C R, Silva M de F

机构信息

Laboratório de Investigação Médica-Parasitologia do Hospital da Clínicas, da Faculdade de Medicina, Universidade de São Paulo, Brasil.

出版信息

Rev Soc Bras Med Trop. 1998 Mar-Apr;31(2):231-3. doi: 10.1590/s0037-86821998000200010.

Abstract

Taking for granted the sensitivity of the Quantitative Buffy Coat (QBC) system, as documented in a murine experimental model, we assayed to detect Trypanosoma cruzi in the peripheral blood of 100 patients with Chagas disease in its chronic phase. By means of the method, no positivity occurred, evently as a consequence of small parasitemias, undetectable by this technique as assessed by the cases in consideration.

摘要

鉴于定量血沉棕黄层(QBC)系统在小鼠实验模型中已被证明具有敏感性,我们试图检测100例慢性期恰加斯病患者外周血中的克氏锥虫。通过该方法,未出现阳性结果,这可能是由于寄生虫血症水平较低,根据所考虑的病例评估,该技术无法检测到。

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