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[非肾性糖尿患儿肾脏浓缩能力的测定]

[Measurement of kidney concentrating ability in children with nonrenal glycosuria].

作者信息

Jährig K, Zöllner H, Giese U

出版信息

Z Gesamte Inn Med. 1976 May 15;31(10):317-21.

PMID:960853
Abstract

In non-renal (diabetic) glucosuria we did not find any statistically real relations between the concentration of glucose in the urine and cryoscopically measured osmolality in children with healthy kidneys. The close negative correlation of the conductance of the urine to the concentration of glucose is not only to be explained by changes of the viscosity, but is an expression of an increased re-absorption of sodium as a result of a compensatory hyperaldosteronism. In renal insufficiency the electrolytic conductibility of the urine is lower than the borderline area of the normal, even when under influence of the glucose excretion the osmolality of the urine is still to be found normal. Thus also on the conditions of a considerable glucosuria we can further judge the concentrating ability of the kidney in diabetes mellitus with the help of the measurement of the conductance of the urine.

摘要

在非肾性(糖尿病性)糖尿中,我们未发现健康肾脏儿童尿液中葡萄糖浓度与冰点渗透压计测量的渗透压之间存在任何统计学上的实际关联。尿液电导率与葡萄糖浓度的密切负相关不仅可以用粘度变化来解释,而且是代偿性醛固酮增多症导致钠重吸收增加的一种表现。在肾功能不全时,即使在葡萄糖排泄的影响下尿液渗透压仍正常,尿液的电解电导率仍低于正常临界范围。因此,即使在有大量糖尿的情况下,我们也可以借助尿液电导率的测量进一步判断糖尿病患者肾脏的浓缩能力。

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1
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