德国人群样本中同时扩增的基因座HLA DQA1、LDLR、GYPA、HBGG、D7S8和GC的群体遗传学研究。
Population genetic study of the simultaneously amplified loci HLA DQA1, LDLR, GYPA, HBGG, D7S8, and GC in a German population sample.
作者信息
Zehner R, Mebs D, Bratzke H
机构信息
Zentrum der Rechtmedizin, J. W. Goethe-Universitat, Frankfurt, Germany.
出版信息
J Forensic Sci. 1998 Jul;43(4):913-4.
A population genetic study of the HLA DQA1 and the "Polymarker" loci LDLR, GYPA, HBG, D7S8, and GC has been performed in a German Caucasian population (Frankfurt am Main area). All loci are in Hardy-Weinberg equilibrium and no unexpected association of loci has been observed. The data of the allele distributions are similar to those of other Caucasian populations. All six loci together have a power of discrimination (PD) of 0.9996 and an exclusion chance in paternity testing of 0.81.
在德国白种人群体（美因河畔法兰克福地区）中进行了一项关于人类白细胞抗原DQA1以及“多标记物”基因座低密度脂蛋白受体（LDLR）、血型糖蛋白A（GYPA）、血红蛋白（HBG）、D7S8和维生素D结合蛋白（GC）的群体遗传学研究。所有基因座均处于哈迪-温伯格平衡，未观察到基因座之间意外的关联。等位基因分布数据与其他白种人群体的数据相似。所有这六个基因座共同具有0.9996的鉴别能力（PD）以及在亲子鉴定中的0.81的排除几率。
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