Urbaszek W
Z Gesamte Inn Med. 1976 Jul 15;31(14):513-20.
Not invasively determined systolic time intervals give references to the left-ventricular function. Restrictions result from the fact that the systolic time intervals are differently influenced by haemodynamic factors. The inotropic state, the pre and after load, the stroke volume, the frequency as well as the sympathoadrenal system have an effect on the systolic time intervals. In addition to this come specific changes of the haemodynamics by valvular lesions and by pharmaca effective on heart and circulation. In as far about established systolic time intervals clinically usable data concerning the disturbed left-ventricular pumping function may be received, was reported on. On principle with certain restrictions a usable separation of groups between normal and disturbed cardiac function is possible. The judgment of the individual case is restricted due to considerable disperions of individual values. Also by an improved measuring technique as well as by tolerance tests the evidence could not convincingly be improved. On the other hand, with the help of the index of isometric contraction after Rentsch (preejection period in the erect position divided by preejection period in lying position) a separation into normal and beginning left ventricular dysfunction is possible in a well reproducible way.
非侵入性测定的收缩期时间间期可为左心室功能提供参考。其局限性在于收缩期时间间期受血流动力学因素的影响各不相同。心肌收缩力状态、前负荷和后负荷、心搏量、心率以及交感肾上腺系统均对收缩期时间间期有影响。除此之外，瓣膜病变以及作用于心脏和循环系统的药物会引起血流动力学的特定变化。关于已确立的收缩期时间间期，已报道了有关左心室泵血功能障碍的临床可用数据。原则上，在一定限制条件下，可以对正常和心脏功能障碍的群体进行有效区分。由于个体值的显著离散，对个体病例的判断受到限制。即使采用改进的测量技术以及耐受试验，证据也未能令人信服地得到改善。另一方面，借助伦奇（Rentsch）提出的等长收缩指数（直立位射血前期除以卧位射血前期），可以很好地重现性地将正常和早期左心室功能障碍区分开来。
