Engum S A, Grosfeld J L
James Whitcomb Riley Hospital for Children, Indiana University, Indianapolis 46202-5200, USA.
Curr Opin Pediatr. 1998 Apr;10(2):123-30. doi: 10.1097/00008480-199804000-00002.
Necrotizing enterocolitis is a relatively common disorder of unknown etiology that primarily affects premature newborns. The majority of babies with necrotizing enterocolitis respond to nonsurgical management, and, despite an increase in the number of premature infants, the surgical mortality rate has improved. This review provides an overview of the current literature covering new developments in etiology, risk factors, pathogenesis, diagnosis, therapy, outcome, and preventable measures related to necrotizing enterocolitis.
坏死性小肠结肠炎是一种病因不明的相对常见疾病，主要影响早产新生儿。大多数坏死性小肠结肠炎患儿对非手术治疗有反应，并且尽管早产儿数量有所增加，但手术死亡率已有所改善。本文综述提供了当前文献的概述，内容涵盖与坏死性小肠结肠炎相关的病因、危险因素、发病机制、诊断、治疗、预后及可预防措施等方面的新进展。
