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健康个体的24小时食管pH监测

[24 hour esophageal pH monitoring in healthy individuals].

作者信息

Manterola C, Garrido L, Muñoz S

机构信息

Departamento de Cirugía, Universidad de la Frontera, Temuco, Chile.

出版信息

Rev Med Chil. 1997 Nov;125(11):1313-8.

PMID:9609052
Abstract

BACKGROUND

Twenty four hour esophageal pH monitoring is considered the gold standard investigation for gastroesophageal reflux disease. This test allows the linkage of symptoms to occurrence of reflux episodes and is used to record the frequency of reflux and the amount of esophageal acid exposure that results from reflux.

AIM

To know the acid esophageal exposure in healthy Chilean subjects.

SUBJECTS AND METHODS

Thirty two asymptomatic volunteers aged 30 to 76 years old (24 female) underwent 24 h esophageal pH monitoring with a digitrapper Mark II Gold (Synectics Medical Stockholm). Total reflux episodes, episodes greater than 5 min, the longest reflux episode, the lapse with pH < 5, the percentage of time with pH < 4 and the score suggested by Johnson and De Mester were analyzed.

RESULTS

There was a mean of 20.9 reflux episodes per subject and 0.1 episodes of more than 5 min. The longest episode lasted 8 min and the mean total time of acid reflux was 10 min/24 h. Total percentage pH below 4 was 0.7% and the mean score was 3.2. No subject reported symptoms during the test.

CONCLUSIONS

For practical purposes, the upper limit of normal acid exposure in Chilean subjects is 2.4%.

摘要

背景

24小时食管pH监测被认为是胃食管反流病的金标准检查。该测试可将症状与反流发作联系起来,并用于记录反流频率以及反流导致的食管酸暴露量。

目的

了解智利健康受试者的食管酸暴露情况。

对象与方法

32名年龄在30至76岁之间的无症状志愿者(24名女性)使用Digitrapper Mark II Gold(瑞典Synectics Medical公司)进行了24小时食管pH监测。分析了总反流发作次数、持续时间超过5分钟的发作次数、最长反流发作时间、pH值小于5的时间段、pH值小于4的时间百分比以及约翰逊和德梅斯特建议的评分。

结果

每位受试者平均有20.9次反流发作,持续时间超过5分钟的发作有0.1次。最长发作持续8分钟,酸反流总平均时间为10分钟/24小时。pH值低于4的总百分比为0.7%,平均评分为3.2。测试期间无受试者报告症状。

结论

出于实际目的,智利受试者正常酸暴露的上限为2.4%。

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