Yambe T, Owada N, Kobayashi S, Sonobe T, Naganuma S, Nanka S, Hashimoto H, Yoshizawa M, Tabayashi K, Takayasu H, Takeda H, Nitta S
Department of Medical Engineering and Cardiology, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Artif Organs. 1998 May;22(5):426-9. doi: 10.1046/j.1525-1594.1998.06148.x.
Aiming at a totally implantable ventricular assist device (VAD), a vibrating flow pump (VFP) was developed in Tohoku University. A transcutaneous energy transmission system (TETS) using an amorphous fiber was developed for the totally implantable VAD system. The VFP works with a higher frequency than the natural heart of a biological system, a frequency of 10-50 Hz. In this research, animal experiments on left heart bypass were performed with healthy goats. Blood from the apex of the left ventricle was received and was sent to the aorta so that an adequate supporting effect of the left heart was provided. In particular, the depression effect of the left ventricle was obvious. As a result, sufficient artificial heart flow was provided. For a totally implantable type VAD, left heart bypass of almost 100% may become necessary in some situations. Therefore, apex approaches of left heart bypass may be desirable. From an anatomical consideration, an apex of the heart is suitable for the VFP of this totally implantable type. In the left heart bypass for which the apex of the heart was used, an almost 100% bypass was possible. This is a requirement that is important when waiting for recovery of sufficient cardiac function. It is also important that left heart circulation is maintained fully by an artificial heart of the complete implantation type. The VFP was considered to be useful as a totally implantable type artificial heart from the results.
针对全植入式心室辅助装置（VAD），东北大学研发了一种振动流泵（VFP）。为全植入式VAD系统开发了一种使用非晶纤维的经皮能量传输系统（TETS）。VFP的工作频率高于生物系统的自然心脏，频率为10 - 50Hz。在本研究中，对健康山羊进行了左心旁路的动物实验。接收来自左心室心尖的血液并将其输送至主动脉，从而提供对左心的充分支持作用。特别是，左心室的减压作用明显。结果，提供了足够的人工心脏血流量。对于全植入式VAD，在某些情况下可能需要几乎100%的左心旁路。因此，左心旁路的心尖入路可能是理想的。从解剖学角度考虑，心脏的心尖适用于这种全植入式的VFP。在使用心脏心尖进行的左心旁路中，几乎可以实现100%的旁路。这是等待足够心脏功能恢复时的一项重要要求。完全植入式人工心脏充分维持左心循环也很重要。从结果来看，VFP被认为作为全植入式人工心脏是有用的。
