Pollak S, Vycudilik W
Z Rechtsmed. 1976 Aug 26;78(2):167-71. doi: 10.1007/BF00204161.
Two cases of poisoning with a double phase effect hypnotic were investigated in respect to the extent to which concentrations of short and medium acting barbiturates (hexobarbital, cyclobarbital) could be used for estimating the duration of poisoning. The analysis of brain turned out to be especially suitable. Increasing the duration of poisoning the ratio of the concentrations was shifted towards the longer acting component. Blood the liver seem to be less informative. The method might be used to estimate the interval between beginning of the poisoning and death in case of intoxication with different acting barbiturates.