Machata G, Vycudilik W
Arch Toxicol. 1975 Feb 14;33(2):115-22. doi: 10.1007/BF00353236.
The use of Amberlite XAD resins for isolation of drugs from blood without preliminary precipitation of proteins is described. Compared with the usual methods of precipitation this method gives better yields and cleaner extracts in a shorter time. In combination with specific methods of detection, e.g. with GC and Nitrogen detector, the use of XAD promises to be efficient in the screening for drugs in the forensic and clinical field.
本文描述了使用Amberlite XAD树脂从血液中分离药物而无需预先沉淀蛋白质的方法。与常规沉淀方法相比,该方法能在更短时间内获得更高的产率和更纯净的提取物。结合特定的检测方法,如气相色谱法和氮检测器,使用XAD树脂有望在法医和临床领域的药物筛查中发挥高效作用。