de Groot K, Wolke J G, Jansen J A
Biomaterials Research Group, University of Leiden, The Netherlands.
Proc Inst Mech Eng H. 1998;212(2):137-47. doi: 10.1243/0954411981533917.
In surgical disciplines where bone has to be repaired, augmented or improved, bone substitutes are essential. Although bone banks, such as Eurotransplant, are founded to supply such substitutes, natural bone is not always adequate. For example, frequently these so-called bone grafts resorb after implantation (1). Further, they cannot be used for joint and tooth replacement, and recently worries have been raised about the transfer of infectious diseases. Therefore, interest has dramatically increased in the use of synthetic materials for replacement of lost or damaged bone tissue. The generic name of these tissue alternatives is biomaterials. A special class of these biomaterials is composed of metallic devices with coatings to improve bone bonding. These specialized coatings used to improve the metallic implant are the topic of this paper.
在必须进行骨修复、增强或改善的外科领域,骨替代物至关重要。尽管像欧洲移植组织这样的骨库已成立以提供此类替代物,但天然骨并不总是足够的。例如,这些所谓的骨移植常常在植入后会被吸收(1)。此外,它们不能用于关节和牙齿置换,并且最近人们对传染病的传播也产生了担忧。因此,使用合成材料替代缺失或受损骨组织的兴趣急剧增加。这些组织替代物的通用名称是生物材料。这类生物材料中的一个特殊类别是带有涂层以改善骨结合的金属装置。用于改善金属植入物的这些特殊涂层就是本文的主题。