Reddy C A, Kao M
J Clin Microbiol. 1978 May;7(5):428-33. doi: 10.1128/jcm.7.5.428-433.1978.
Acid metabolic products of 23 strains of human and animal pathogenic corynebacteria, representing eight different species, were determined by gas chromatography. The results showed that the species examined were metabolically heterogeneous and could be presumptively identified based on the acid products produced. Corynebacterium equi did not produce any acids; C. renale produced lactate; and C. pyogenes produced major amounts of lactate, variable amounts of acetate, and minor amounts of succinate and pyruvate. C. kutscheri produced propionate and lactate as major products and pyruvate and oxalacetate as minor products. C. diphtheriae and C. pseudotuberculosis produced major amounts of propionate, acetate, and formate. In addition, C. pseudotuberculosis produced major amounts of pyruvate and minor amounts of succinate, lactate, and oxalacetate, whereas C. diphtheriae strains produced minor but variable amounts of lactate, succinate, fumarate, pyruvate, and oxalacetate. C. bovis produced aicd products similar to those of C. pyogenes but was readily distinguishable from the latter by the lack of hemolysis on blood agar, colony morphology, catalase reaction, and biochemicals. C. suis characteristically produced major amounts of ethanol, acetate, and formate and minor amounts of lactate and succinate but no propionate.
通过气相色谱法测定了代表8个不同种的23株人和动物致病性棒状杆菌的酸性代谢产物。结果表明，所检测的菌种在代谢上具有异质性，可根据产生的酸性产物进行初步鉴定。马棒状杆菌不产生任何酸；肾棒状杆菌产生乳酸；化脓棒状杆菌产生大量乳酸、可变数量的乙酸以及少量琥珀酸和丙酮酸。库氏棒状杆菌产生丙酸和乳酸作为主要产物，丙酮酸和草酰乙酸作为次要产物。白喉棒状杆菌和假结核棒状杆菌产生大量丙酸、乙酸和甲酸。此外，假结核棒状杆菌产生大量丙酮酸以及少量琥珀酸、乳酸和草酰乙酸，而白喉棒状杆菌菌株产生少量但可变数量的乳酸、琥珀酸、富马酸、丙酮酸和草酰乙酸。牛棒状杆菌产生的酸性产物与化脓棒状杆菌相似，但通过在血琼脂上不溶血、菌落形态、过氧化氢酶反应和生化特性可容易地与后者区分开来。猪棒状杆菌典型地产生大量乙醇、乙酸和甲酸以及少量乳酸和琥珀酸，但不产生丙酸。
