Arden S B, Chang W H, Barksdale L
J Bacteriol. 1972 Dec;112(3):1206-12. doi: 10.1128/jb.112.3.1206-1212.1972.
In Corynebacterium diphtheriae and closely related neuraminidase-producing corynebacteria, we have found an N-acetylneuraminate (NAN) lyase activity which cleaves NAN into N-acetyl-d-mannosamine and, presumably, pyruvate. In vitro, these lyases can be shown to synthesize NAN. A survey of representative corynebacteria, "plant pathogenic corynebacteria," mycobacteria, and nocardias revealed that only those corynebacteria closely related to C. diphtheriae exhibited both neuraminidase and NAN lyase activities.
在白喉棒状杆菌及与之密切相关的产神经氨酸酶棒状杆菌中，我们发现了一种N - 乙酰神经氨酸（NAN）裂解酶活性，该酶可将NAN裂解为N - 乙酰 - D - 甘露糖胺以及推测的丙酮酸。在体外实验中，这些裂解酶可合成NAN。对具有代表性的棒状杆菌、“植物致病棒状杆菌”、分枝杆菌和诺卡氏菌的调查显示，只有那些与白喉棒状杆菌密切相关的棒状杆菌同时具有神经氨酸酶和NAN裂解酶活性。
