Berge T, Linell F
Acta Pathol Microbiol Scand A. 1976 Jul;84(4):322-30.
The frequency of carcinoids was studied in a 12-year-period (1958-1969) in Malmö, a town with a population of 220,000 at the beginning of the period and 250,000 at the end of it. Of all persons who had died in Malmö, 46 per cent were necropsied in the first year of the study and 70 per cent in the last (altogether 62.6 per cent). The series was examined in a uniform way at one department of pathology. Carcinoid tumours were found in 1.22 per cent (199 patients) of patients comprised in the entire necropsy series (16,294 autopsies). Bronchial carcinoid accounted for 0.1 percent, the remaining lesions were found in the digestive tract. About 90 per cent of the carcinoids were found incidentally at necropsy. During the same period, 44 carcinoids were diagnosed in surgical specimens examined in Malmö. The average annual frequency of carcinoid in the entire series was about 8.4 per 100,000 inhabitants, which is about 7 times as high as that recorded in the National Cancer Register applying to the whole of Sweden. The value of such country-wide reports is discussed. The carcinoid syndrome is extremely rare and was observed only once during the entire 12-year-period. The localization, frequency of metastases and sex-distribution of carcinoids are described and discussed in detail.
在马尔默进行了一项为期12年（1958 - 1969年）的类癌发病率研究。该城镇在研究开始时人口为22万，结束时为25万。在马尔默所有死亡的人中，46%在研究的第一年进行了尸检，最后一年为70%（总计62.6%）。整个尸检系列（16294例尸检）由一个病理科以统一方式进行检查。在整个尸检系列的患者中，1.22%（199例患者）发现了类癌肿瘤。支气管类癌占0.1%，其余病变见于消化道。约90%的类癌是在尸检时偶然发现的。同一时期，在马尔默检查的手术标本中诊断出44例类癌。整个系列中类癌的年平均发病率约为每10万居民8.4例，约为适用于瑞典全国的国家癌症登记处记录发病率的7倍。讨论了此类全国性报告的价值。类癌综合征极为罕见，在整个12年期间仅观察到1例。详细描述并讨论了类癌的定位、转移频率和性别分布。
