Erhardt L R, Sjögren A
Acta Med Scand. 1976;200(1-2):127-130. doi: 10.1111/j.0954-6820.1976.tb08207.x.
In an attempt to diagnose ventricular mural thrombi complicating acute myocardial infarction (AMI), 80 patients have been given 100 muCi 125I-labelled fibrinogen after admission to a CCU. Precordial radioactivity was recorded for the following 6 days over four sites corresponding to chest leads CR1-CR4. A sustained rise in radioactivity of at least 15% of initial recordings was classed as type A pattern, a minor rise or flattened response as type B pattern and a rapid decrease as type C pattern; 28% showed a type A, 19% a type B and 54% a type C pattern. There was no significant difference between the groups in incidence of pericardial friction rub but when patients with suspected pericarditis (as evidenced by characteristic pains) were added, pericarditis was significantly overrepresented in the type A group. Smaller infarctions (SGOT less than 100 U/1) were significantly more common in patients with a type C decay pattern. No differences were noted between the groups as regards type and site of the infarction. A sustained rise in precordial radioactivity after an AMI may be an indication of mural thrombosis but the influence of other factors secondary to an infarction, e.g. pericarditis, cannot be determined at present.
为了诊断并发急性心肌梗死（AMI）的心室壁血栓，80例患者在进入冠心病监护病房（CCU）后接受了100微居里的125I标记纤维蛋白原。在接下来的6天里，在与胸导联CR1 - CR4相对应的四个部位记录心前区放射性。放射性持续升高至少为初始记录的15%被归类为A型模式，轻微升高或平坦反应为B型模式，快速下降为C型模式；28%表现为A型，19%为B型，54%为C型。心包摩擦音的发生率在各组之间没有显著差异，但当加入疑似心包炎的患者（以特征性疼痛为证）时，A型组的心包炎明显过多。梗死面积较小（谷草转氨酶小于100 U/1）的患者在C型衰减模式中明显更为常见。在梗死类型和部位方面，各组之间未发现差异。急性心肌梗死后心前区放射性持续升高可能提示壁血栓形成，但目前尚无法确定梗死继发的其他因素（如心包炎）的影响。
