Erhardt L R, Unge G, Boman G
Am Heart J. 1976 May;91(5):592-8. doi: 10.1016/s0002-8703(76)80144-5.
The presence of radioactivity in coronary arterial thrombi was studied at necropsy by autoradiography in 12 patients with acute myocardial infarction. Seven patients had been given 125I-and five patients 131I-labeled fibrinogen. With a short interval (less than 10 hours) between onset of symptoms and injection of fibrinogen the entire thrombus was radioactive in four of five patients, whereas with longer time intervals only parts or none of the thrombus contained detectable radioactivity. The findings give further evidence that thrombus formation in acute myocardial infarction probably is a slow process and that the major part of the thrombus may form after the onset of necrosis.
通过尸检放射自显影术研究了12例急性心肌梗死患者冠状动脉血栓中的放射性情况。7例患者接受了125I标记的纤维蛋白原，5例患者接受了131I标记的纤维蛋白原。症状发作与注射纤维蛋白原之间的间隔时间较短（少于10小时）时，5例患者中有4例的整个血栓具有放射性，而间隔时间较长时，只有部分血栓或无血栓含有可检测到的放射性。这些发现进一步证明，急性心肌梗死中的血栓形成可能是一个缓慢的过程，并且血栓的主要部分可能在坏死发作后形成。
