Yokogoshi H, Mochizuki M, Saitoh K
Laboratory of Nutritional Biochemistry, School of Food and Nutritional Sciences, University of Shizuoka, Japan.
Biosci Biotechnol Biochem. 1998 Apr;62(4):816-7. doi: 10.1271/bbb.62.816.
Following the administration of theanine, the brain tryptophan content significantly increased or tended to increase, but the contents of serotonin and 5-hydroxyindole acetic acid (5HIAA) decreased. The use of inhibitors of serotonin metabolism enable us to speculate that theanine reduced serotonin synthesis and also increased serotonin degradation in the brain.