Pérez Alenza M D, Peña L, Nieto A I, Castaño M
Departmento de Patología Animal II, Facultad de Veterinaria, Universidad Complutense de Madrid, Spain.
Ann Ist Super Sanita. 1997;33(4):581-5.
In the present study, clinical and reproductive variables and pathological features were evaluated as prognostic factors in canine mammary tumor disease. Seventy-four female dogs free of distant metastases at diagnosis were followed-up during a period of 18 months after the surgical excision of mammary nodules. Age at presentation, tumor size, lymph node involvement, histological malignant grade and nuclear grade were proven to act as variables able to predict the overall survival time in dogs with mammary neoplasms. Disease free survival time was associated to the age, the presence of multiple malignant tumors, tumor size and ulceration of the skin.
在本研究中，对临床和生殖变量以及病理特征进行评估，将其作为犬乳腺肿瘤疾病的预后因素。对74只诊断时无远处转移的雌性犬在乳腺结节手术切除后的18个月期间进行随访。结果证明，就诊时的年龄、肿瘤大小、淋巴结受累情况、组织学恶性分级和核分级可作为预测乳腺肿瘤犬总生存时间的变量。无病生存时间与年龄、多发恶性肿瘤的存在、肿瘤大小和皮肤溃疡有关。
