Ficarra V, Zanon G, D'Amico A, Mofferdin A, Tallarigo C, Malossini G
Cattedra e Divisione Clinicizzata di Urologia, Università degli Studi di Verona.
Arch Ital Urol Androl. 1998 Apr;70(2):57-64.
Idiopathic varicocele can compromise the spermatogenetic function of the testicle and associate with alterations of the semen quality. The treatment of varicocele stops the progress of testicular damage and improves spermatogenesis and semen parameters. These are the main alternatives to the traditional surgical treatment of varicocele retrograde percutaneous occlusion of the internal spermatic vein using sclerosing agents and embolizing devices (either separately or in combination), microsurgical ligation via inguinal or sub-inguinal approach, laparoscopic ligation and, more recently, antegrade scrotal sclerotherapy. None of these techniques can be considered the "gold standard" therapy. Literature does not point out any significant difference between them, either considering the absence of reflux percentage, or the improvement of semen quality, or the pregnance rate. Therefore cost comparison may be a valid criterion in the choice of treatment for varicocele correction. The total cost of the surgical retroperitoneal unilateral ligation of the internal spermatic vein is 968,805 Lire, while for the bilateral ligation it is 1,118,285 Lire. The costs of sclerotherapy and percutaneous embolization are respectively of 698,750 Lire and 1,708,950 Lire. The combination of the two techniques amounts to 1,918,230 Lire. Laparoscopic bilateral ligation costs 2,437,935 Lire. Antegrade scrotal sclerotherapy costs 191,035 Lire if unilateral, 216,580 Lire if bilateral. After considering these data we can say that antegrade scrotal sclerotherapy is the first choice economically in the treatment of both unilateral and bilateral varicocele.
特发性精索静脉曲张可损害睾丸的生精功能,并与精液质量改变相关。精索静脉曲张的治疗可阻止睾丸损伤的进展,并改善精子发生和精液参数。这些是精索静脉曲张传统手术治疗的主要替代方法,即使用硬化剂和栓塞装置经皮逆行闭塞精索内静脉(单独或联合使用)、经腹股沟或腹股沟下途径进行显微外科结扎、腹腔镜结扎,以及最近出现的顺行阴囊硬化疗法。这些技术均不能被视为“金标准”疗法。无论是从无反流百分比、精液质量改善还是妊娠率来看,文献均未指出它们之间存在任何显著差异。因此,成本比较可能是选择精索静脉曲张矫正治疗方法的一个有效标准。精索内静脉腹膜后单侧结扎的总成本为968,805里拉,双侧结扎则为1,118,285里拉。硬化疗法和经皮栓塞的成本分别为698,750里拉和1,708,950里拉。两种技术联合使用的成本为1,918,230里拉。腹腔镜双侧结扎的成本为2,437,935里拉。顺行阴囊硬化疗法单侧治疗成本为191,035里拉,双侧治疗成本为216,580里拉。考虑到这些数据后,我们可以说顺行阴囊硬化疗法在单侧和双侧精索静脉曲张的治疗中在经济上是首选。