Yoshida K, Miyazaki H, Aizawa H, Tsuruta N, Sugio K, Hara N
Research Institute for Diseases of the Chest, Faculty of Medicine, Kyushu University.
Nihon Kokyuki Gakkai Zasshi. 1998 Feb;36(2):192-6.
We report an extremely rare case of intrapulmonary lymphangioma. A 41-year-old woman was admitted to our hospital for complete medical evaluation of a pulmonary nodule on chest X-ray, which was found during an annual check-up. Chest radiograph showed a well-circumscribed spherical mass adjacent to the right border of the heart in the right lower lung field. Although a cystic tumor of the lung was suspected based on computed tomogram and magnetic resonance imaging findings, a histologic diagnosis could not be made on transbronchial biopsy. In addition, the nodule had increased in size compared with a chest X-ray taken 1 year previously. Enucleation was performed. Histological examination revealed numerous cysts with thin walls lined by a single layer of cells in which immunoreactivity to von Willebrand factor was weakly positive. Intrapulmonary lymphangioma was subsequently diagnosed.
我们报告一例极其罕见的肺内淋巴管瘤病例。一名41岁女性因年度体检时胸部X线发现肺部结节而入院进行全面医学评估。胸部X线片显示右下肺野靠近心脏右缘有一个边界清晰的球形肿块。尽管根据计算机断层扫描和磁共振成像结果怀疑是肺囊性肿瘤，但经支气管活检无法做出组织学诊断。此外，与1年前的胸部X线片相比，该结节大小有所增大。遂进行了摘除术。组织学检查发现大量薄壁囊肿，内衬单层细胞，对血管性血友病因子的免疫反应弱阳性。随后诊断为肺内淋巴管瘤。
