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关于人类分娩过程中母体催产素释放及静脉注射酒精影响的观察

Observations on maternal oxytocin release during human labor and the effect of intravenous alcohol administration.

作者信息

Gibbens G L, Chard T

出版信息

Am J Obstet Gynecol. 1976 Sep 15;126(2):243-6. doi: 10.1016/0002-9378(76)90283-0.

DOI:10.1016/0002-9378(76)90283-0
PMID:961764
Abstract

Serial blood samples were obtained from 97 women in spontaneous labor, and oxytocin levels were determined by a sensitive and highly specific radioimmunoassay. The following observations were made: (1) The hormone is released in a series of "spurts"; (2) the peak levels achieved are usually 2 to 5 muU per milliliter and never exceed 12.5 muU per milliliter; (3) the frequency of spurt release increases as labor progresses, reaching a maximum in the second stage; (4) the frequency of spurt release is reduced during intravenous infusion of alcohol at levels which produce no obvious effect on uterine activity.

摘要

从97名自然分娩的女性身上采集了系列血样,并通过一种灵敏且高度特异的放射免疫测定法测定了催产素水平。得出了以下观察结果:(1)该激素以一系列“脉冲”形式释放;(2)达到的峰值水平通常为每毫升2至5毫微单位,且从未超过每毫升12.5毫微单位;(3)脉冲释放的频率随着产程进展而增加,在第二产程达到最高;(4)在静脉输注酒精期间,脉冲释放频率降低,而此时酒精水平对子宫活动无明显影响。

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Observations on maternal oxytocin release during human labor and the effect of intravenous alcohol administration.关于人类分娩过程中母体催产素释放及静脉注射酒精影响的观察
Am J Obstet Gynecol. 1976 Sep 15;126(2):243-6. doi: 10.1016/0002-9378(76)90283-0.
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