14C-1-棕榈酸酯在体内掺入兔胎儿脂质的情况。

Incorporation of 14C-1-palmitate into rabbit fetal lipids in vivo.

作者信息

Biezenski J J

出版信息

Am J Obstet Gynecol. 1976 Oct 1;126(3):356-64. doi: 10.1016/0002-9378(76)90550-0.

Abstract

14C-1-palmitate was injected into rabbit fetuses in utero. Fetal liver, blood, carcass, and placenta collected after 15, 60, 180, and 360 minutes were analyzed for radioactivity in lipid classes. Incorporation differed with tissue and lipid. Highest total early specific activity was detected in plasma but later liver displayed the most extensive incorporation. Phospholipid incorporation was more rapid in all tissues than that of other glycerides. Plasma triglycerides did not display any radioactivity for 3 hours. Results point to multicentric origin of plasma lipids. Ready utilization of the palmitate indicates that maternal fatty acid transfer plays an important role in fetal lipid hemeostasis.

摘要

将14C-1-棕榈酸盐注入子宫内的兔胎儿体内。在15、60、180和360分钟后收集胎儿的肝脏、血液、胴体和胎盘，分析脂质类别中的放射性。摄取情况因组织和脂质而异。血浆中早期总比活性最高，但后来肝脏显示出最广泛的摄取。所有组织中磷脂的摄取都比其他甘油酯更快。血浆甘油三酯在3小时内未显示任何放射性。结果表明血浆脂质的多中心起源。棕榈酸盐的快速利用表明母体脂肪酸转移在胎儿脂质稳态中起重要作用。