Stone D L, Kenyon K R, Stark W J
Am J Ophthalmol. 1976 Sep;82(3):450-8. doi: 10.1016/0002-9394(76)90494-3.
The corneas of three patients with keratoconus were examined by light and electron microscopy within approximately four months after onset of severe hydrops. The rupture and detachment of Descemet's membrane resulted in formation of extensive ledges. New endothelium completely resurfaced the exposed posterior stroma and the corresponding anterior aspect of the ledges. The endothelium also regenerated considerable basement membrane. In one case, clustered endothelium near the free end of the ledge appeared to have undergone fibrous metaplasia with secretion of extensive fibrillar and basement membrane material.
对三名圆锥角膜患者在严重角膜水肿发作后约四个月内进行了光镜和电镜检查。后弹力层的破裂和脱离导致形成广泛的嵴。新的内皮细胞完全覆盖了暴露的后基质和嵴的相应前表面。内皮细胞还再生了相当数量的基底膜。在一个病例中，嵴自由端附近聚集的内皮细胞似乎发生了纤维化生，并分泌了大量的纤维状和基底膜物质。
