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纽约州对尸体肾移植多重挂牌的禁令的影响。

The effects of New York state's ban on multiple listing for cadaveric kidney transplantation.

作者信息

White A J, Ozminkowski R J, Hassol A, Dennis J M, Murphy M

机构信息

Abt Health Care Research Foundation, Cambridge, MA 02138, USA.

出版信息

Health Serv Res. 1998 Jun;33(2 Pt 1):205-22.

Abstract

OBJECTIVE

To study the effectiveness of a 1990 ban by New York state on entry to more than one waiting list for a cadaver kidney transplant, and the impact of the ban on equity in access to transplantation.

DATA SOURCES

(1) Waiting list files from the Organ Procurement and Transplantation Network, (2) the Health Care Financing Administration's Medicare Program Management and Medical Information System, and (3) U.S. Census Public Use Files.

STUDY DESIGN

Multivariate hazard models were used to estimate the impact of the ban of the overall odds of multiple listing and on the odds of multiple listing at in-state and out-of-state transplant centers. After estimating the relationship between multiple listing and subsequent transplantation, we used simulation techniques to estimate the effects of a complete multiple listing ban on group waiting time differentials. Independent variables included demographic/socioeconomic characteristics, measures of ESRD severity, general transplantation suitability, measures that affect the likelihood of finding a good donor organ, and measures of the productivity of the transplant/dialysis center.

PRINCIPAL FINDINGS

The ban was associated with a 66 percent reduction in the rate of multiple listing for New York patients, and multiple listing at in-state transplant centers declined by 87 percent. Simulation results suggested that even a completely effective ban would produce only small, mixed equity effects.

CONCLUSIONS

While the ban was effective in reducing the proportion of patients who registered at multiple transplant centers, taken together the results suggest that banning multiple listing is not likely to result in large improvements in equity in access to transplantation.

摘要

目的

研究纽约州1990年实施的禁止加入多个尸体肾移植等候名单的禁令的有效性,以及该禁令对移植可及性公平性的影响。

数据来源

(1)器官获取与移植网络的等候名单文件,(2)医疗保健财务管理局的医疗保险计划管理与医疗信息系统,以及(3)美国人口普查公共使用文件。

研究设计

使用多变量风险模型来估计该禁令对重复登记总体几率的影响,以及对州内和州外移植中心重复登记几率的影响。在估计了重复登记与后续移植之间的关系后,我们使用模拟技术来估计完全禁止重复登记对组间等候时间差异的影响。自变量包括人口统计学/社会经济特征、终末期肾病严重程度指标、一般移植适宜性、影响找到合适供体器官可能性的指标,以及移植/透析中心的生产力指标。

主要发现

该禁令使纽约患者的重复登记率降低了66%,州内移植中心的重复登记率下降了87%。模拟结果表明,即使是完全有效的禁令也只会产生微小的、混合的公平效应。

结论

虽然该禁令有效地降低了在多个移植中心登记的患者比例,但综合结果表明,禁止重复登记不太可能使移植可及性公平性得到大幅改善。

相似文献

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Multiple listing in kidney transplantation.肾脏移植中的多重列表。
Am J Kidney Dis. 2010 Apr;55(4):717-25. doi: 10.1053/j.ajkd.2009.11.022. Epub 2010 Feb 26.

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