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纽约州对尸体肾移植多重挂牌的禁令的影响。

The effects of New York state's ban on multiple listing for cadaveric kidney transplantation.

作者信息

White A J, Ozminkowski R J, Hassol A, Dennis J M, Murphy M

机构信息

Abt Health Care Research Foundation, Cambridge, MA 02138, USA.

出版信息

Health Serv Res. 1998 Jun;33(2 Pt 1):205-22.

PMID:9618668
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1070261/
Abstract

OBJECTIVE

To study the effectiveness of a 1990 ban by New York state on entry to more than one waiting list for a cadaver kidney transplant, and the impact of the ban on equity in access to transplantation.

DATA SOURCES

(1) Waiting list files from the Organ Procurement and Transplantation Network, (2) the Health Care Financing Administration's Medicare Program Management and Medical Information System, and (3) U.S. Census Public Use Files.

STUDY DESIGN

Multivariate hazard models were used to estimate the impact of the ban of the overall odds of multiple listing and on the odds of multiple listing at in-state and out-of-state transplant centers. After estimating the relationship between multiple listing and subsequent transplantation, we used simulation techniques to estimate the effects of a complete multiple listing ban on group waiting time differentials. Independent variables included demographic/socioeconomic characteristics, measures of ESRD severity, general transplantation suitability, measures that affect the likelihood of finding a good donor organ, and measures of the productivity of the transplant/dialysis center.

PRINCIPAL FINDINGS

The ban was associated with a 66 percent reduction in the rate of multiple listing for New York patients, and multiple listing at in-state transplant centers declined by 87 percent. Simulation results suggested that even a completely effective ban would produce only small, mixed equity effects.

CONCLUSIONS

While the ban was effective in reducing the proportion of patients who registered at multiple transplant centers, taken together the results suggest that banning multiple listing is not likely to result in large improvements in equity in access to transplantation.

摘要

目的

研究纽约州1990年实施的禁止加入多个尸体肾移植等候名单的禁令的有效性,以及该禁令对移植可及性公平性的影响。

数据来源

(1)器官获取与移植网络的等候名单文件,(2)医疗保健财务管理局的医疗保险计划管理与医疗信息系统,以及(3)美国人口普查公共使用文件。

研究设计

使用多变量风险模型来估计该禁令对重复登记总体几率的影响,以及对州内和州外移植中心重复登记几率的影响。在估计了重复登记与后续移植之间的关系后,我们使用模拟技术来估计完全禁止重复登记对组间等候时间差异的影响。自变量包括人口统计学/社会经济特征、终末期肾病严重程度指标、一般移植适宜性、影响找到合适供体器官可能性的指标,以及移植/透析中心的生产力指标。

主要发现

该禁令使纽约患者的重复登记率降低了66%,州内移植中心的重复登记率下降了87%。模拟结果表明,即使是完全有效的禁令也只会产生微小的、混合的公平效应。

结论

虽然该禁令有效地降低了在多个移植中心登记的患者比例,但综合结果表明,禁止重复登记不太可能使移植可及性公平性得到大幅改善。

相似文献

1
The effects of New York state's ban on multiple listing for cadaveric kidney transplantation.纽约州对尸体肾移植多重挂牌的禁令的影响。
Health Serv Res. 1998 Jun;33(2 Pt 1):205-22.
2
Multiple listing for organ transplantation: autonomy unbounded.器官移植的多重登记:无限制的自主权。
Kennedy Inst Ethics J. 1992 Mar;2(1):43-59. doi: 10.1353/ken.0.0046.
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Unequal access to cadaveric kidney transplantation in California based on insurance status.加利福尼亚州基于保险状况的尸体肾移植获取机会不平等。
Health Serv Res. 1999 Oct;34(4):879-900.
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Allocation of deceased donor kidneys for transplantation: opinions of patients with CKD.deceased供体肾脏移植的分配:慢性肾脏病患者的观点
Am J Kidney Dis. 2005 Nov;46(5):949-56. doi: 10.1053/j.ajkd.2005.07.031.
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Development of a central matching system for the allocation of cadaveric kidneys: a simulation of clinical effectiveness versus equity.尸体肾分配中央匹配系统的开发:临床有效性与公平性的模拟
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Association of the kidney allocation system with dialysis exposure before deceased donor kidney transplantation by preemptive wait-listing status.预先候补等待状态与供体死亡前接受肾移植患者透析暴露的肾脏分配系统的相关性。
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Obesity and gender-biased access to deceased donor kidney transplantation.肥胖与性别偏见对接受已故供体肾移植的影响。
Nephrol Dial Transplant. 2020 Jan 1;35(1):184-189. doi: 10.1093/ndt/gfz100.
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Multiple listing in kidney transplantation.肾脏移植中的多重列表。
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引用本文的文献

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Am J Transplant. 2022 Jul;22(7):1813-1822. doi: 10.1111/ajt.17044. Epub 2022 Apr 6.
2
Association between Longer Travel Distance for Transplant Care and Access to Kidney Transplantation and Graft Survival in the United States.美国范围内,移植护理的旅行距离与肾移植机会和移植物存活率的关联。
J Am Soc Nephrol. 2021 May 3;32(5):1151-1161. doi: 10.1681/ASN.2020081242. Epub 2021 Mar 12.
3
Multiple listing in lung transplant candidates: A cohort study.肺移植候选人的多重列表:一项队列研究。
Am J Transplant. 2019 Apr;19(4):1098-1108. doi: 10.1111/ajt.15124. Epub 2018 Oct 16.
4
Outcomes of Multiple Listing for Adult Heart Transplantation in the United States: Analysis of OPTN Data From 2000 to 2013.美国成人心脏移植多重登记的结果:对2000年至2013年器官共享联合网络数据的分析
JACC Heart Fail. 2015 Dec;3(12):933-41. doi: 10.1016/j.jchf.2015.07.012. Epub 2015 Nov 11.
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Multiple listings as a reflection of geographic disparity in liver transplantation.作为肝移植地理差异反映的多重登记。
J Am Coll Surg. 2014 Sep;219(3):496-504. doi: 10.1016/j.jamcollsurg.2014.03.048. Epub 2014 May 2.

本文引用的文献

1
Racial differences in access to kidney transplantation.肾移植可及性方面的种族差异。
Health Care Financ Rev. 1995 Winter;17(2):89-103.
2
The impact of comorbid and sociodemographic factors on access to renal transplantation.共病因素和社会人口学因素对肾移植可及性的影响。
JAMA. 1993 Feb 3;269(5):603-8.
3
Access to heart and liver transplantation in the late 1980s.20世纪80年代末心脏和肝脏移植的可及性。
Med Care. 1993 Nov;31(11):1027-42. doi: 10.1097/00005650-199311000-00005.
4
The distribution of HLA antigens and phenotypes among donors and patients in the UNOS registry.
Transplantation. 1994 Nov 27;58(10):1119-30.
5
Access to kidney transplantation. Has the United States eliminated income and racial differences?肾移植的可及性。美国是否消除了收入和种族差异?
Arch Intern Med. 1988 Dec;148(12):2594-600. doi: 10.1001/archinte.148.12.2594.
6
Factors affecting the waiting time of cadaveric kidney transplant candidates in the United States.影响美国尸体肾移植候选者等待时间的因素。
JAMA. 1992 Jan 8;267(2):247-52.