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High human herpesvirus 8 seroprevalence in the homosexual population in Switzerland.瑞士同性恋人群中人类疱疹病毒8型血清阳性率较高。
J Clin Microbiol. 1998 Jun;36(6):1784-6. doi: 10.1128/JCM.36.6.1784-1786.1998.
2
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Prevalence of Kaposi's sarcoma associated herpesvirus infection measured by antibodies to recombinant capsid protein and latent immunofluorescence antigen.通过针对重组衣壳蛋白和潜伏免疫荧光抗原的抗体测量卡波西肉瘤相关疱疹病毒感染的患病率。
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Virology. 1999 Apr 10;256(2):381-92. doi: 10.1006/viro.1999.9674.
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Identification of antigenic proteins encoded by human herpesvirus 8 and seroprevalence in the general population and among patients with and without Kaposi's sarcoma.人类疱疹病毒8编码的抗原蛋白鉴定及其在普通人群以及卡波西肉瘤患者与非患者中的血清流行率
J Virol. 2000 Apr;74(8):3478-85. doi: 10.1128/jvi.74.8.3478-3485.2000.

本文引用的文献

1
Kaposi's sarcoma associated herpes virus (KSHV/HHV 8): epidemiology, molecular biology and tissue distribution.卡波西肉瘤相关疱疹病毒（KSHV/HHV 8）：流行病学、分子生物学及组织分布
Mol Pathol. 1997 Feb;50(1):4-8. doi: 10.1136/mp.50.1.4.
2
Detection of human herpesvirus 8 DNA in Kaposi's sarcoma lesions and peripheral blood of human immunodeficiency virus-positive patients and correlation with serologic measurements.在人类免疫缺陷病毒阳性患者的卡波西肉瘤病灶和外周血中检测人类疱疹病毒8型DNA及其与血清学检测的相关性。
J Infect Dis. 1997 Jul;176(1):84-93. doi: 10.1086/514043.
3
Detection of serum antibodies to a Kaposi's sarcoma-associated herpesvirus-specific peptide.检测针对卡波西肉瘤相关疱疹病毒特异性肽的血清抗体。
J Infect Dis. 1997 May;175(5):1071-9. doi: 10.1086/516444.
4
Detection of antibodies against viral capsid proteins of human herpesvirus 8 in AIDS-associated Kaposi's sarcoma.在艾滋病相关卡波西肉瘤中检测针对人疱疹病毒8型病毒衣壳蛋白的抗体
J Mol Med (Berl). 1997 Feb;75(2):145-52. doi: 10.1007/s001090050099.
5
Prevalence of Kaposi's sarcoma associated herpesvirus infection measured by antibodies to recombinant capsid protein and latent immunofluorescence antigen.通过针对重组衣壳蛋白和潜伏免疫荧光抗原的抗体测量卡波西肉瘤相关疱疹病毒感染的患病率。
Lancet. 1996 Oct 26;348(9035):1133-8. doi: 10.1016/S0140-6736(96)07560-5.
6
Changing seroepidemiology of HHV-8.人疱疹病毒8型血清流行病学的变化
Lancet. 1996 Oct 26;348(9035):1110-1. doi: 10.1016/S0140-6736(05)65265-8.
7
Detection of herpesvirus-like DNA by nested PCR on archival skin biopsy specimens of various forms of Kaposi sarcoma.通过巢式聚合酶链反应在各种形式卡波西肉瘤的存档皮肤活检标本中检测疱疹病毒样DNA。
J Clin Pathol. 1996 Aug;49(8):631-3. doi: 10.1136/jcp.49.8.631.
8
Establishment and characterization of a primary effusion (body cavity-based) lymphoma cell line (BC-3) harboring kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) in the absence of Epstein-Barr virus.在无爱泼斯坦-巴尔病毒的情况下，建立并鉴定一株携带卡波西肉瘤相关疱疹病毒（KSHV/HHV-8）的原发性渗出性（基于体腔）淋巴瘤细胞系（BC-3）。
Blood. 1996 Oct 1;88(7):2648-54.
9
Antibodies to human herpesvirus type 8 in the general population and in Kaposi's sarcoma patients.普通人群及卡波西肉瘤患者中针对人类疱疹病毒8型的抗体
Lancet. 1996 Sep 28;348(9031):858-61. doi: 10.1016/S0140-6736(96)03240-0.
10
KSHV antibodies among Americans, Italians and Ugandans with and without Kaposi's sarcoma.患有和未患卡波西肉瘤的美国人、意大利人和乌干达人中的卡波西肉瘤相关疱疹病毒抗体
Nat Med. 1996 Aug;2(8):925-8. doi: 10.1038/nm0896-925.

瑞士同性恋人群中人类疱疹病毒8型血清阳性率较高。

High human herpesvirus 8 seroprevalence in the homosexual population in Switzerland.

作者信息

Regamey N, Cathomas G, Schwager M, Wernli M, Harr T, Erb P

机构信息

Institute for Medical Microbiology, University of Basel, Switzerland.

出版信息

J Clin Microbiol. 1998 Jun;36(6):1784-6. doi: 10.1128/JCM.36.6.1784-1786.1998.

DOI:10.1128/JCM.36.6.1784-1786.1998
PMID:9620422
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC104922/
Abstract

The seroprevalence of human herpesvirus 8 (HHV-8) in the Swiss population was investigated. By enzyme-linked immunosorbent assay, sera reactive to the recombinant HHV-8 antigen orf 65.2 were found in 24% of human immunodeficiency virus (HIV)-positive patients without and in 92% of HIV-positive patients with Kaposi's sarcoma. Surprisingly, 20% of homosexual HIV-negative men, versus only 7% of heterosexual HIV-negative individuals and 5% of blood donors, had antibodies to HHV-8.

摘要

对瑞士人群中人类疱疹病毒8型（HHV-8）的血清流行率进行了调查。通过酶联免疫吸附测定法，在24%未患卡波西肉瘤的人类免疫缺陷病毒（HIV）阳性患者以及92%患卡波西肉瘤的HIV阳性患者中，发现血清对重组HHV-8抗原orf 65.2呈反应性。令人惊讶的是，20%的同性恋HIV阴性男性体内有HHV-8抗体，而异性恋HIV阴性个体中这一比例仅为7%，献血者中为5%。