Zotikov E A, Vasil'eva M N
Klin Lab Diagn. 1998 Apr(4):36-8.
Sera of thirty patients with acute and chronic immune neutropenias for different target cells: polymorphonuclear leukocytes (PMNL), macrophages, T and B lymphocytes are studied. An increase of the level of antigranulocyte antibodies is associated with a decrease of PMNL count, whereas a decrease of these antibodies' level is paralleled by an increase of the neutrophil count. It is noteworthy that the sera of patients with acute neutropenias contain autoantibodies similar to antibodies to CD13 antigen, which react mainly with the neutrophils. The sera of patients with chronic neutropenias contain antibodies similar to anti-CD45 antibodies and react with all target cells.
对30例急性和慢性免疫性中性粒细胞减少症患者针对不同靶细胞（多形核白细胞（PMNL）、巨噬细胞、T和B淋巴细胞）的血清进行了研究。抗粒细胞抗体水平升高与PMNL计数降低相关，而这些抗体水平降低则与中性粒细胞计数增加平行。值得注意的是，急性中性粒细胞减少症患者的血清中含有类似于抗CD13抗原抗体的自身抗体，主要与中性粒细胞发生反应。慢性中性粒细胞减少症患者的血清中含有类似于抗CD45抗体的抗体，并与所有靶细胞发生反应。
