Dyzyk H M, Shumeha I S, Tarasenko A O, Patoka V V
Lik Sprava. 1998 Jan-Feb(1):109-12.
Blood serum content was studied of specific antistaphylococcal antibodies (staphylolysins) in 576 donors immunized with staphylococcal anatoxin with the purpose of obtaining an antistaphylococcal plasma and antistaphylococcal immunoglobulin to be used in clinical settings. 292 donors had been immunized and examined prior to 1986, 284--after 1986 (before 1994). Comparison of the immune responses in the above periods of time permitted finding out that 13.03% of immunized donors responded to the antigenic stimulus by such paradoxical reaction as disappearance of specific antibodies; the number of persons-active respondents has gotten reduced from 17.12% to 5.98% as has the number of individuals having the baseline level of staphylolysins (1-2 ME/ml). The changes were at their greatest in donors with group A (II) blood.
为了获取可用于临床的抗葡萄球菌血浆和抗葡萄球菌免疫球蛋白，对576名用葡萄球菌类毒素免疫的献血者的血清中特异性抗葡萄球菌抗体（葡萄球菌溶血素）含量进行了研究。292名献血者在1986年之前接受了免疫和检查，284名在1986年之后（1994年之前）。对上述时间段内的免疫反应进行比较后发现，13.03%的免疫献血者对抗原刺激的反应是出现特异性抗体消失这种矛盾反应；积极反应者的数量从17.12%减少到了5.98%，葡萄球菌溶血素基线水平（1-2 ME/ml）的个体数量也减少了。这些变化在A型（II）血的献血者中最为明显。
