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Immunocytochemical localization of mu-opioid receptor in primary afferent neurons containing substance P or calcitonin gene-related peptide. A light and electron microscope study in the rat.

作者信息

Li J L, Ding Y Q, Li Y Q, Li J S, Nomura S, Kaneko T, Mizuno N

机构信息

Department of Anatomy and K.K. Leung Brain Research Centre, Fourth Military Medical University, Xi'an 710032, China.

出版信息

Brain Res. 1998 Jun 1;794(2):347-52. doi: 10.1016/s0006-8993(98)00332-1.

DOI:10.1016/s0006-8993(98)00332-1
PMID:9622672
Abstract

Co-expression of mu-opioid receptor-like immunoreactivity (MOR-LI) with substance P (SP)- or calcitonin gene-related (CGRP)-LI was observed in rat trigeminal and dorsal root ganglion neurons. In particular, MOR-LI was found in axon terminals with SP- or CGRP-LI in laminae I and II of the medullary and spinal dorsal horns. MOR may be implicated in modulation of release of SP and CGRP from primary sensory afferents.

摘要

相似文献

1
Immunocytochemical localization of mu-opioid receptor in primary afferent neurons containing substance P or calcitonin gene-related peptide. A light and electron microscope study in the rat.
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2
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Distribution of axons showing calcitonin gene-related peptide- and/or substance P-like immunoreactivity in the sensory trigeminal nuclei of the cat.猫三叉神经感觉核中显示降钙素基因相关肽和/或P物质样免疫反应性的轴突分布。
Neurosci Res. 1991 Jul;11(2):119-33. doi: 10.1016/0168-0102(91)90050-9.
8
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Morphine treatment induced calcitonin gene-related peptide and substance P increases in cultured dorsal root ganglion neurons.吗啡处理可诱导培养的背根神经节神经元中降钙素基因相关肽和P物质增加。
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[Substance P and/or calcitonin gene-related peptide immunoreactive neurons in dorsal root ganglia possibly involved in the transmission of nociception in rat penile frenulum].[背根神经节中P物质和/或降钙素基因相关肽免疫反应性神经元可能参与大鼠阴茎系带伤害性感受的传递]
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