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[吞咽困难作为黏液性水肿的一种症状]

[Dysphagia as a symptom of myxedema].

作者信息

Reiss M

机构信息

Klinik und Poliklinik für Hals-Nasen-Ohren-Heilkunde, Universitätsklinikum Dresden.

出版信息

Praxis (Bern 1994). 1998 Apr 29;87(18):627-9.

PMID:9623334
Abstract

We present a 79 year old female patient with dysphagia since two years. She showed also a lack of initiation and dysphonia. In the region of the larynx an edema was found and the tongue was hypertrophied. The X-ray examination demonstrated a dilated esophagus without impairment of the passage way. Esophagoscopy showed also important edema in the hypopharynx and the entry into the esophagus. The TSH-0 was 74.45 mmu/l, the T3 0.23 and the T4 was 24 nmol/l. Scintigraphically an only cherry-stone small region with active thyroid tissue was revealed. Severe hypothyroidism responsible for secondary dysphagia was diagnosed. L-Thyroxin was administered (150 micrograms/d). There was a dramatical improvement. The signs of edema and the dysphagia decreased. The examination a half year later demonstrated a patient without any dysphagia or edema. The symptom dysphagia is defined and an interdisciplinary approach emphasized.

摘要

我们报告一位79岁女性患者,她两年来一直有吞咽困难。她还表现出启动困难和发音障碍。在喉部区域发现水肿,舌头肥大。X线检查显示食管扩张,但通道未受损害。食管镜检查也显示下咽和食管入口处有明显水肿。促甲状腺激素(TSH)为74.45 mU/L,三碘甲状腺原氨酸(T3)为0.23,甲状腺素(T4)为24 nmol/L。闪烁扫描仅发现一个樱桃核大小的活跃甲状腺组织区域。诊断为严重甲状腺功能减退导致继发性吞咽困难。给予左旋甲状腺素(150微克/天)。病情有显著改善。水肿体征和吞咽困难减轻。半年后的检查显示患者没有任何吞咽困难或水肿。对吞咽困难症状进行了定义,并强调了多学科方法。

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