以构音障碍为表现的甲状腺功能减退症。
Hypothyroidism presenting with dysarthria.
作者信息
El-Shafie Kawther T
机构信息
Family and Community Medicine Department, College of Medicine, Sultan Qaboos University, Al-Khoud, Sultanate of Oman.
出版信息
J Family Community Med. 2003 May;10(2):55-7.
Hypothyroidism is a common endocrine disorder with characteristic clinical symptoms and signs. Typical symptoms of hypothyroidism are lethargy, cold intolerance, slowing of intellectual and motor activity, decreased appetite, weight gain, and dry skin. A 39-year-old female presented to the clinic with dysarthria as the chief symptom. Subsequent questions revealed that other symptoms were confined to the otolaryngeal region, which were episodes of mild dysphonia, dysphagia, sleep apnea, and snoring. Laboratory data revealed marked hypothyroidism and positive tests for antithyroglobulin and antimicrosomal antibodies. After administration of thyroxin, the dysarthria and the other symptoms rapidly disappeared. Dysarthria may be the presenting symptom of hypothyroidism and can be resolved after hormone replacement therapy.
甲状腺功能减退症是一种常见的内分泌疾病，具有典型的临床症状和体征。甲状腺功能减退症的典型症状包括嗜睡、不耐寒、智力和运动活动迟缓、食欲减退、体重增加以及皮肤干燥。一名39岁女性以构音障碍为主要症状前来就诊。随后的询问发现，其他症状局限于耳鼻喉区域，包括轻度发音困难、吞咽困难、睡眠呼吸暂停和打鼾发作。实验室检查结果显示明显的甲状腺功能减退，抗甲状腺球蛋白和抗微粒体抗体检测呈阳性。给予甲状腺素后，构音障碍和其他症状迅速消失。构音障碍可能是甲状腺功能减退症的首发症状，激素替代治疗后可得到缓解。
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