Lurie S, Frenkel E, Tuvbin Y
Department of Obstetrics and Gynecology, Assaf-Harofeh Medical Center, Zerifin, Israel.
Gynecol Obstet Invest. 1998;45(4):229-31. doi: 10.1159/000009973.
To describe leukocyte count and differential distribution in preeclampsia and uncomplicated pregnancy.
Blood samples were obtained from 46 consecutive preeclamptic patients and 46 controls with uncomplicated pregnancy. Thirty met the criteria for mild preeclampsia and 16 for severe. The blood was tested within 1 h of venepuncture. An aliquot of the blood was tested in the Cell-Dyn 2000 for complete blood cell count.
The absolute neutrophil count was significantly elevated in preeclamptic patients as compared with that of controls with uncomplicated pregnancy (9,410.1+/-3,066.9 vs. 7,498.6+/-2,354.0 x 10(6)/l, p < 0.05). In neutrophils, the elevation was more prominent in severe preeclamptic patients as compared with mild preeclamptic patients (10,658.8+/-3520.4 vs. 8,694.4+/-2,561.9 x 10(6)/l, p < 0.05). The absolute lymphocyte and eosinophil counts declined in patients with preeclampsia as compared with uncomplicated pregnancy, whereas monocyte and basophil counts did not differ.
Our results suggest that preeclampsia is associated with an increase in the absolute neutrophil count.
描述子痫前期及正常妊娠时白细胞计数及分类分布情况。
连续采集46例子痫前期患者及46例正常妊娠对照者的血样。其中30例符合轻度子痫前期标准，16例符合重度标准。采血后1小时内进行检测。取一份血样用Cell-Dyn 2000进行全血细胞计数检测。
子痫前期患者的绝对中性粒细胞计数显著高于正常妊娠对照者（9,410.1±3,066.9对7,498.6±2,354.0×10⁶/l，p<0.05）。在中性粒细胞方面，重度子痫前期患者的升高比轻度子痫前期患者更显著（10,658.8±3520.4对8,694.4±2,561.9×10⁶/l，p<0.05）。子痫前期患者的绝对淋巴细胞和嗜酸性粒细胞计数低于正常妊娠者，而单核细胞和嗜碱性粒细胞计数无差异。
我们的结果表明，子痫前期与绝对中性粒细胞计数增加有关。
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