阿替洛尔过量服用48小时后出现电机械分离：氯化钙的效用

Electromechanical dissociation 48 hours after atenolol overdose: usefulness of calcium chloride.

作者信息

Pertoldi F, D'Orlando L, Mercante W P

机构信息

Intensive Care Unit, General Hospital, Pordenone, Italy.

出版信息

Ann Emerg Med. 1998 Jun;31(6):777-81. doi: 10.1016/s0196-0644(98)70241-0.

DOI:10.1016/s0196-0644(98)70241-0

PMID:9624322

Abstract

Electromechanical dissociation (EMD) occurred in a 20-year-old woman 48 hours after an overdose of atenolol, despite intensive treatment of the beta-blocker poisoning (gastric lavage, charcoal, glucagon, epinephrine, atropine, correction of electrolyte abnormalities, administration of fluids, cardiac pacing, and mechanical ventilation). Administration of calcium chloride during EMD repeatedly restored blood pressure. Therefore it may have a role to play in management of atenolol overdose.

摘要

一名20岁女性在过量服用阿替洛尔48小时后发生了电机械分离（EMD），尽管对β受体阻滞剂中毒进行了强化治疗（洗胃、活性炭、胰高血糖素、肾上腺素、阿托品、纠正电解质异常、补液、心脏起搏和机械通气）。在电机械分离期间给予氯化钙可反复恢复血压。因此，它可能在阿替洛尔过量的治疗中发挥作用。